Characteristics Associated with Autism Spectrum Disorder Risk in Individuals with Down Syndrome.
In Down syndrome, low IQ and daily-living skills plus high problem behaviors signal greater autism symptom load.
01Research in Context
What this study did
Channell et al. (2019) looked at people with Down syndrome. They asked which traits flag a higher chance of also meeting autism criteria.
They checked IQ scores, daily-living skills, and problem behaviors. Then they compared these scores to autism symptom checklists.
What they found
Lower IQ and weaker self-care skills went hand-in-hand with more autism features. More tantrums, self-harm, or repetitive actions also pointed to higher autism risk.
How this fits with other research
Cook et al. (2021) extends this picture. They show that kids who have both Down syndrome and autism speak in shorter, simpler phrases than kids with Down syndrome alone.
Porter et al. (2008) seems to disagree. In adults with intellectual disability, autism did not add extra mental-health risk once ability level and Down syndrome were counted. The gap is age and method: Moore studied children and used direct skill tests, while A et al. tracked adult service records.
Schaaf et al. (2015) back up Moore on behavior: across teens with autism, harsher autism symptoms predict more self-injury, just as Moore saw in the Down-syndrome group.
Why it matters
If you assess a child with Down syndrome, do not assume delays are "just the DS." Check adaptive scores and note any rising problem behaviors. When both are low, add an autism screener to your plan and prepare for speech and behavior goals that are more intense.
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02At a glance
03Original abstract
We examined autism spectrum disorder (ASD) risk in a large national sample of 203 individuals with Down syndrome, 6-25 years old, to determine the association of ASD risk with age, sex, IQ, adaptive behaviors, and maladaptive behaviors. We used a two-pronged approach by (1) considering ASD symptomatology continuously across the sample of individuals with DS and examining associations with each characteristic, and (2) dichotomizing our sample into high and low ASD risk groups and comparing groups on each characteristic. The pattern of results was largely similar across both types of analyses. ASD symptomatology/risk was negatively associated with IQ and adaptive behaviors and positively associated with certain types of maladaptive behaviors. Clinical implications for screening and therapeutic purposes are discussed.
Journal of autism and developmental disorders, 2019 · doi:10.1007/s10803-019-04074-1