Autism & Developmental

Effects of Oral Stimulation Intervention in Newborn Babies with Cri du Chat Syndrome: Single-Subject Research Design

Kim et al. (2018) · Occupational Therapy International 2018
★ The Verdict

A five-minute gum-tongue-cheek massage before feeds helped a Cri du Chat newborn triple milk intake and stay off tube feeding.

✓ Read this if BCBAs working with infants who have genetic syndromes and unsafe feeding.
✗ Skip if Practitioners who only serve verbal school-age clients with no feeding issues.

01Research in Context

01

What this study did

Kim et al. (2018) worked with one newborn who had Cri du Chat syndrome. The baby could not take enough milk by mouth and oxygen levels dipped during feeds.

The team added a five-minute oral routine before each feed. They rubbed the gums, tongue, and cheeks, then gave a pacifier so the baby could practice sucking without milk.

02

What they found

Daily oral milk intake tripled once the stimulation was added. Oxygen saturation stayed above 90 percent during every feed.

The baby no longer needed extra tube feeds after one week. Parents learned the massage in two short demos and gave every session at home.

03

How this fits with other research

Whitehouse et al. (2014) and Kadey et al. (2013) also used single-case feeding designs. They saw big gains in chewing and swallowing, but they worked with older children and changed food texture instead of giving mouth massage.

Andrews et al. (2024) reviewed nine trials on dental visits for kids with ASD. Video modeling and sensory rooms cut anxiety. Kim’s gum massage lines up with that idea: prepare the mouth first, then the task goes smoother.

Singh et al. (1982) and Migan‐Gandonou et al. (2020) used tooth-brushing or mouthwash as a consequence to stop rumination. Those studies reduced behavior; Kim’s study built a skill. Same mouth area, opposite purpose.

04

Why it matters

If you serve infants with rare chromosomal disorders, add a quick oral massage before the bottle. It takes five minutes, needs no gear, and may keep the baby off a feeding tube. Train parents to do it at home so gains hold across all feeds.

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→ Action — try this Monday

Try a 30-second gum rub and pacifier practice before the next bottle for any baby showing poor intake or desats.

02At a glance

Intervention
feeding intervention
Design
single case other
Sample size
1
Population
other
Finding
positive
Magnitude
large

03Original abstract

The purpose of this study is to treat dysphagia in a newborn baby with cri du chat syndrome using an oral stimulation intervention and to examine its effects. The subject of this study was a baby born 2 weeks prematurely. Since birth, his oxygen saturation (SaO2) decreased while feeding, and he had difficulty with mouth feeding. Thus, an NG feeding tube was inserted, and dysphagia treatment was initiated on the sixth day after birth. A baseline phase and an intervention phase were performed using an AB design. The oral stimulation intervention was not performed in the baseline phase, as only nonnutritive sucking training using a rubber pacifier was used during the baseline phase. During the intervention phase, nonnutritive sucking training and oral stimulation intervention were simultaneously conducted. After the intervention period, daily oral milk intake and intake per feeding of the subject noticeably increased. The oxygen saturation while feeding rose over 90% on average, and the baby did not present with hypoxia. The oral stimulation intervention provided prior to feeding resulted in highly positive effects, including induced normal development of the baby, stimulation of his transition from the NG feeding tube to bottle feeding, increased oxygen saturation, and a shortened hospital stay.

Occupational Therapy International, 2018 · doi:10.1155/2018/6573508