Trajectories of diurnal cortisol in mothers of children with autism and other developmental disabilities: relations to health and mental health.
Flat daily cortisol curves spot the autism moms most at risk—screen early and move support resources there first.
01Research in Context
What this study did
The team tracked moms of kids with autism or other delays for two years. They took saliva four times a day to map each mom’s daily cortisol slope.
They also asked about stress, mood, and health every six months. The goal was to see if different stress patterns show up in the hormone data.
What they found
Two clear cortisol tracks appeared. Thirty-seven percent of moms had the normal dip from morning to night. Sixty-three percent showed a flat, blunted curve.
The flat-curve moms scored higher on parenting stress and reported more illnesses. Their stress hormone system looked worn out.
How this fits with other research
Fucà et al. (2025) also found moms under pressure, but in Down syndrome. The two studies seem to clash—who is most stressed? The answer is both groups are, yet the driver is the child’s diagnosis, not the moms themselves.
Takahashi et al. (2023) widened the lens to Chinese moms of kids with ID. They linked high stress to harsher parenting styles, extending the target finding that stress shows up in biology and behavior.
Northup et al. (1991) showed social support protects autism moms’ mental health. Capio et al. (2013) now adds a body-stress marker, giving you two levers: boost support and check cortisol.
Why it matters
You can’t fix what you don’t measure. A quick saliva kit at intake can flag the moms whose stress systems are already maxed out. Pair those data with brief stress surveys and you will know who needs parent training first, who needs respite, and who may benefit from medical referral before burnout hits.
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02At a glance
03Original abstract
This study used a stress biomarker, diurnal cortisol, to identify how elevated stress in mothers of children and adults with autism and other disabilities relates to their health and mental health. Based on semi-parametric, group-based trajectory analysis of 91 mothers, two distinctive cortisol trajectories emerged: blunted (63 %) or steep (37 %). Mothers in the blunted (vs. steep) trajectory had higher stress levels, lower health ratings, and 89 % of mothers of children with autism, and 53 % with other disabilities, belonged to this trajectory. Atypical cortisol awakening responses and evening rises were differentially associated with anxiety, depression, health problems and employment status. Stress-reducing interventions are needed for parents of children with autism and other disabilities that include biomarkers as indices of risk or treatment outcome.
Journal of autism and developmental disorders, 2013 · doi:10.1007/s10803-013-1791-1