Incomplete Gestation has an Impact on Cognitive Abilities in Autism Spectrum Disorder.
Even early-term birth drops IQ and language scores in kids with ASD, so check gestational age when you plan lessons.
01Research in Context
What this study did
The team looked at the kids with autism. Some were born early-term (37-38 weeks). Some were moderate-late preterm (32-36 weeks). The rest were full-term (39+ weeks).
All kids took the same IQ and language tests. The doctors also rated their autism symptoms. Then the scores were lined up by birth week.
What they found
Early-term and preterm kids with ASD scored lower on every test. The gap was 6-10 points for both talking and non-talking tasks.
Autism symptom scores stayed the same across groups. Shorter pregnancy hurt thinking skills, not social symptoms.
How this fits with other research
Eklöf et al. (2019) extends this picture backward. They scanned extremely preterm newborns who later got ASD. Those babies already showed uneven brain folds linked to language. The brain signs appear first; the low scores show up later.
Vassos et al. (2023) seems to clash but really doesn’t. They found that by age 10, extremely preterm and term-born kids with ASD looked alike on social symptoms. Brayette et al. (2019) saw the same thing. The new twist: parents in M et al. recalled fewer repetitive hand or word rituals in the preterm group. Different question, same core story—gestation changes cognition more than it changes core autism traits.
Kuang et al. (2025) builds a tool from this idea. They fed BSID-III scores from 6-24 months into a computer model. The model spots very preterm babies who will later get ASD with a large share certainty. Maëva’s finding gave them the reason to try.
Why it matters
When a child with ASD is born even a little early, expect lower cognitive scores even if autism behaviors look typical. Use this info when you set language and learning goals. Start skills teaching earlier and monitor progress more often. Share the gestational-age fact with teachers and parents so they understand why extra practice time may be needed.
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02At a glance
03Original abstract
Extreme prematurity is known as a risk factor for autism spectrum disorder (ASD). However, the association between prematurity and ASD, for children born moderately and late preterm (MLPT) and those born early term (ET), is less established. This retrospective study aimed to characterize the phenotypic characteristics (i.e. behavioral profile and cognitive abilities) of 254 children with ASD, between 3 and 15 years of age, born MLPT (19 children), ET (60 children) and full term (175 children). MLPT and ET births do not modify ASD symptomatology, but modify cognitive development. The results highlight that incomplete gestation, i.e., MLPT or ET, has a negative impact on both verbal and nonverbal cognitive abilities, in children with neurodevelopmental vulnerability.
Journal of autism and developmental disorders, 2019 · doi:10.1007/s10803-019-04105-x