Children with cerebral palsy and periventricular white matter injury: does gestational age affect functional outcome?
Among children with CP plus PWMI, those born after 34 weeks move, handle objects, and communicate more easily than those born earlier.
01Research in Context
What this study did
McGeown et al. (2013) looked at kids who have cerebral palsy plus a brain injury called PWMI. They asked whether being born earlier than 34 weeks changes how well these kids move, walk, use their hands, and talk.
The team used a quasi-experimental design. They split the children into two groups: those born at or before 34 weeks and those born after 34 weeks. Then they compared the two groups on everyday skills.
What they found
Children with CP and PWMI who were born after 34 weeks had milder problems in every area tested. They moved better, walked better, used their hands better, and communicated better than the early-born group.
The study found a positive link between later birth age and better function. Even a few extra weeks in the womb seemed to help these kids.
How this fits with other research
Levin et al. (2014) seems to disagree. They saw high motor-impairment rates in all preterm Brazilian school-agers, not just the early ones. The key difference is that S et al. looked at every preterm child, while R et al. studied only kids who already have CP plus PWMI. When you zoom in on that smaller group, the 34-week cutoff matters.
Pino et al. (2017) extend the story. They show that preterm kids with spastic diplegia also have hidden executive-function problems. So motor gains after 34 weeks may not tell the whole story; check attention and planning skills too.
Franki et al. (2020) add a caution. Their review found that MRI lesion type does not yet predict motor severity in CP. Gestational age gives useful clues, but brain pictures still can’t tell us exactly how well a child will walk or talk.
Why it matters
If you work with a child who has CP plus PWMI, note the birth history. Kids born after 34 weeks may need less intense motor support and can aim for higher independence goals. Still, screen for executive-function issues and use local motor curves, not just Western charts, to set realistic targets.
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02At a glance
03Original abstract
This study aimed to determine differences in functional profiles and movement disorder patterns in children aged 4-12 years with cerebral palsy (CP) and periventricular white matter injury (PWMI) born >34 weeks gestation compared with those born earlier. Eligible children born between 1999 and 2006 were recruited through the Victorian CP register. Functional profiles were determined using the Gross Motor Function Classification System (GMFCS), Manual Abilities Classification System (MACS), Communication Function Classification System (CFCS), Functional Mobility Scale (FMS) and Bimanual Fine Motor Function (BFMF). Movement disorder and topography were classified using the Surveillance of Cerebral Palsy in Europe (SCPE) classification. 49 children born >34 weeks (65% males, mean age 8 y 9 mo [standard deviation (SD) 2 y 2 mo]) and 60 children born ≤ 34 weeks (62% males, mean age 8 y 2 mo [SD 2 y 2 mo]) were recruited. There was evidence of differences between the groups for the GMFCS (p=0.003), FMS 5, 50 and 500 (p=0.003, 0.002 and 0.012), MACS (p=0.04) and CFCS (p=0.035), with a greater number of children born ≤ 34 weeks more severely impaired compared with children born later. Children with CP and PWMI born >34 weeks gestation had milder limitations in gross motor function, mobility, manual ability and communication compared with those born earlier.
Research in developmental disabilities, 2013 · doi:10.1016/j.ridd.2013.05.030