Autism & Developmental

Effectiveness of music therapy in children with autism spectrum disorder: A systematic review and meta-analysis.

Ke et al. (2022) · Frontiers in Psychiatry 2022
★ The Verdict

Music therapy gives autistic kids a tiny nudge in social reactions—use it as a brief social primer, not a stand-alone treatment.

✓ Read this if BCBAs running early-intervention or preschool groups who want low-cost social priming activities.
✗ Skip if Clinicians seeking large, lasting cuts in core autism symptoms or language delays.

01Research in Context

01

What this study did

Ke et al. (2022) pooled eight randomized trials of music therapy for autistic children. They looked for changes in social reactions, symptom severity, adaptive behavior, and speech.

02

What they found

Only social reactions showed a small, significant bump. Core autism symptoms, daily living skills, and language did not move. The gain is real but tiny.

03

How this fits with other research

Anonymous (2025) later surveyed the same trials and called the evidence 'mixed,' not positive. The newer review supersedes Ke et al. because it adds three years of extra data and lowers the confidence rating.

Zhou et al. (2025) ran a fresh 12-week RCT and found medium social-communication gains. Their larger effect may come from a tight group protocol, showing the meta-average can hide bigger wins under the right conditions.

Finnigan et al. (2010) foreshadowed this field: one preschooler with autism responded far better to music-based social games than to identical non-music games. The single-case result aligns with the small group trend Ke et al. later quantified.

04

Why it matters

If you already use music, keep it short and social—expect only a gentle boost, not a core-symptom fix. Pair songs with turn-taking or peer imitation to target the one area with solid evidence. Track social initiations during and right after sessions; if you see no uptick within two weeks, re-allocate time to stronger interventions.

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→ Action — try this Monday

Open your next social-skills group with a two-minute call-and-response song, count peer eye contact before and after—keep the routine only if you see a jump.

02At a glance

Intervention
other
Design
meta analysis
Sample size
608
Population
autism spectrum disorder
Finding
weakly positive
Magnitude
small

03Original abstract

This study was to investigated the efficacy of music therapy (MT) in children with autism spectrum disorder (ASD) via a meta-analysis that comprehensively evaluated data from all eligible research in this field. Systematic review and meta-analysis. A systematic search of the PubMed, Embase, and Cochrane Library databases from inception to October 2021 to identify studies that administered MT to children with ASD. Eight randomized controlled trials (RCTs) including 608 participants met the inclusion criteria. The meta-analysis showed that MT was associated with a significant increase in social reactions among children with ASD (standardized mean difference (SMD) = 0.24, 95% confidence interval (CI) [0.03, 0.46], I2 = 0%, P = 0.03). However, MT did not elicit a significant increase in symptom severity (SMD = 0.17, 95% CI [−0.04,0.38], I2 = 0%,P = 0.12), social adaptive behavior (SMD = 0.02, 95% CI [−0.44,0.48], I2 = 0%,P = 0.93) or speech (SMD = 0.04, 95% CI [−0.39, 0.47], I2 = 0%, P = 0.86) in children with ASD. MT can improve social skills in children with ASD; however, there does not seem to be a consensus on the persistence of its effects. These findings can inform clinical practice. Promoting the use of MT in children with ASD and improving its symptoms are the ultimate goals.

Frontiers in Psychiatry, 2022 · doi:10.3389/fpsyt.2022.905113