Autism & Developmental

Association Between Prematurity and Diagnosis of Neurodevelopment Disorder: A Case-Control Study.

Soncini et al. (2020) · Journal of autism and developmental disorders 2020
★ The Verdict

Brazilian kids born even a little early are over three times more likely to be diagnosed with autism or ADHD.

✓ Read this if BCBAs doing intake or parent training with young children
✗ Skip if Clinicians who only serve adults with no developmental history

01Research in Context

01

What this study did

Doctors compared Brazilian kids who have autism or ADHD with kids who do not. They asked mothers about birth history and looked at hospital records.

Any child born before 37 weeks counted as premature. The team used stats to see if early birth alone raised the odds of later diagnosis.

02

What they found

Prematurity tripled-plus the chance of an autism or ADHD label. The link stayed strong even after removing other medical issues.

03

How this fits with other research

van Timmeren et al. (2016) saw no extra risk from Cesarean or induced birth in 13 000 UK kids. The studies seem to clash, but they looked at different events: the UK paper asked how the baby came out, while the Brazilian paper asked how early.

Dodds et al. (2011) mined a giant Canadian set and also tied several prenatal issues to autism. Their data set is bigger and older, so the new study extends the story to Brazil and spotlights prematurity.

Weiss et al. (2001) used the same case-control method in kids with tuberous sclerosis and found mild birth problems did not predict autism severity. Together the papers hint that timing of birth matters more than general obstetric hassle.

04

Why it matters

When you meet a family, ask about weeks of gestation. If the child arrived early, share that this raises the odds of autism or ADHD and explain why early monitoring makes sense. Use the number to justify extra screening, earlier ABA intake, or tighter pediatric follow-up.

Free CEUs

Want CEUs on This Topic?

The ABA Clubhouse has 60+ free CEUs — live every Wednesday. Ethics, supervision & clinical topics.

Join Free →
→ Action — try this Monday

Add one question to your intake form: 'Weeks pregnant at birth?' Flag any answer under 37 for closer developmental watch.

02At a glance

Intervention
not applicable
Design
case study
Population
autism spectrum disorder, adhd
Finding
positive

03Original abstract

The aim of this study is to investigate the association between prematurity and diagnosis of neurodevelopmental disorders (ND) (attention deficit/hyperactivity disorder [ADHD] or autism spectrum disorder [ASD]) in Brazilian children and adolescents. Case-control study based on medical records data from a specialized outpatient clinic. Prematurity was defined as gestational age less than 37 weeks. Prematurity was independently associated with diagnosis of a ND (adjusted odds ratio [AOR] 3.46, 95% CI 1.15 - 7.92), as well as with ADHD and ASD diagnosis after a multiple logistic regression analysis. These findings from Brazilian patients are related to what is found in the literature worldwide. Efforts to modify risk factors, such as prematurity, may impact incidence reduction of both ADHD and ASD.

Journal of autism and developmental disorders, 2020 · doi:10.1007/s10803-019-04235-2