Assessment & Research

Heavy metal in children's tooth enamel: related to autism and disruptive behaviors?

Abdullah et al. (2012) · Journal of autism and developmental disorders 2012
★ The Verdict

Baby-tooth metal levels do not explain autism or tantrums, so skip this costly test.

✓ Read this if BCBAs who field parent questions about toxins, chelation, or special labs.
✗ Skip if Clinicians already focused on skill acquisition rather than medical causes.

01Research in Context

01

What this study did

Scientists shaved tiny bits of baby teeth from three groups of kids. One group had autism. One group had lots of tantrums but no autism. The last group was typically developing.

They tested the enamel for lead, mercury, and manganese. These metals can build up before birth. The team wanted to know if metal levels matched later behavior problems.

02

What they found

Metal levels were the same across all three groups. Kids with autism did not have more lead or mercury in their teeth. High tantrums did not link to higher metal either.

The study found no signal that heavy metals in enamel explain autism or disruptive behavior.

03

How this fits with other research

Lundström et al. (2014) also found no autism–behavior link. They tracked Swedish siblings and saw autism did not raise later crime risk. Both papers show autism alone does not drive externalizing problems.

Sievers et al. (2020) did find one birth risk that matters. They showed premature babies had 3.5 times higher odds of later autism or ADHD. So some prenatal events matter, but tooth metals do not.

Lung et al. (2018) and Boudreau et al. (2015) looked at assisted reproduction. Like the metal study, they found no extra autism risk from ART. The pattern is clear: many suspected birth exposures fail to predict autism once properly tested.

04

Why it matters

You can stop asking parents to test baby teeth for heavy metals. The data say it will not guide treatment. Focus your energy on evidence-based risks like prematurity and on skill-building programs that actually help.

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When a parent mentions heavy-metal testing, share this null finding and pivot to a skill assessment.

02At a glance

Intervention
not applicable
Design
case control
Population
autism spectrum disorder, neurotypical
Finding
null

03Original abstract

To examine possible links between neurotoxicant exposure and neuropsychological disorders and child behavior, relative concentrations of lead, mercury, and manganese were examined in prenatal and postnatal enamel regions of deciduous teeth from children with Autism Spectrum Disorders (ASDs), high levels of disruptive behavior (HDB), and typically developing (TD) children. Using laser ablation inductively coupled plasma mass spectrometry, we found no significant differences in levels of these neurotoxicants for children with ASDs compared with TD children, but there was marginal significance indicating that children with ASDs have lower manganese levels. No significant differences emerged between children with HDB and TD children. The current findings challenge the notion that perinatal heavy metal exposure is a major contributor to the development of ASDs and HDB.

Journal of autism and developmental disorders, 2012 · doi:10.1007/s10803-011-1318-6