Autism & Developmental

Regression versus no regression in the autistic disorder: developmental trajectories.

Bernabei et al. (2007) · Journal of autism and developmental disorders 2007
★ The Verdict

Autistic preschoolers who never lose skills race ahead in language and play, while those who regress need stronger, longer support.

✓ Read this if BCBAs doing early-intake assessments or running preschool ABA classrooms.
✗ Skip if Clinicians who only work with verbal school-age fluency programs.

01Research in Context

01

What this study did

Heslop et al. (2007) watched two groups of preschoolers with autism. One group lost skills they once had. The other group never lost skills.

They tracked language, play, and communication every year from age two to six.

02

What they found

Kids who never regained moved ahead faster. Their words, play, and back-and-forth talk grew more each year.

Kids who had lost skills earlier stayed behind in the same areas.

03

How this fits with other research

Boterberg et al. (2019) later saw the same split. They added that regressed children also show more repetitive play and rigid routines in grade school.

Hu et al. (2024) gave both groups one year of ABA. Young non-regressed kids made big jumps. Young regressed kids made only small jumps. The pattern fits: the gap seen by P et al. is hard to close even with treatment.

Tan et al. (2021) pooled 75 studies and found about one in three children with autism lose skills. That number places the regressed group in P et al. inside a common subtype, not a rare edge case.

04

Why it matters

Screen early for any loss of words, gestures, or play. If you see it, plan denser teaching hours and add parent coaching. Track both groups separately in your data. Expect slower progress for the regressed cluster and celebrate small wins to keep families engaged.

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Flag any history of lost words in your intake, then schedule extra language trials and parent coaching right away.

02At a glance

Intervention
not applicable
Design
pre post no control
Sample size
40
Population
autism spectrum disorder
Finding
positive
Magnitude
medium

03Original abstract

Developmental regression is a complex phenomenon which occurs in 20-49% of the autistic population. Aim of the study was to assess possible differences in the development of regressed and non-regressed autistic preschoolers. We longitudinally studied 40 autistic children (18 regressed, 22 non-regressed) aged 2-6 years. The following developmental areas were considered fundamental in the first years of life, and were assessed at ages 2, 3, 4, 5, and 6: receptive and expressive language, communicative and request modalities, play activities, and mental age. Children who regressed showed lower mean performances than those who did not regress and, in the time intervals considered, non-regressed children improved their ratings in the above mentioned variables significantly more than regressed children.

Journal of autism and developmental disorders, 2007 · doi:10.1007/s10803-006-0201-3