Onset patterns prior to 36 months in autism spectrum disorders.
Skill loss before age two is a red flag for severe autism later—start intensive services immediately.
01Research in Context
What this study did
The team looked at the toddlers with ASD. They split them into three groups based on how symptoms first showed up.
Group one lost skills they already had. Group two stopped gaining new skills. Group three never lost skills and kept learning.
Doctors tracked each child from first visit until age three. They scored language, play, and social skills every few months.
What they found
Kids who lost skills looked almost typical at 12 months. By 36 months they had the most severe autism symptoms.
Kids who plateaued had some early delays but stayed better than the loss group.
Kids with no loss and no plateau had the mildest symptoms at age three.
How this fits with other research
Tan et al. (2021) pooled 75 studies and found about 30 percent of kids with ASD lose skills. This backs up Sharp et al. (2010) numbers.
Waizbard-Bartov et al. (2022) followed kids to age 11 and showed half changed severity after age three. This extends the target finding that early pattern predicts later outcome.
Solomon et al. (2018) tracked IQ from age two to eight. Some kids with regression gained 30 points while others lost ground. This shows the same start can lead to very different paths.
Son et al. (2013) found girls with ASD show more regression than boys. This adds a sex lens to the target findings.
Why it matters
If a child loses words or play skills at 18-24 months, act fast. Start full assessment within weeks, not months. Push for intensive services even if the child seemed fine last month. Track progress monthly and adjust plans as needed.
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02At a glance
03Original abstract
The present study investigated differences among children with three different patterns of autism symptom onset: regression, plateau, and no loss and no plateau. Cross-sectional data were collected from parents of children aged 3-17 years with an autism spectrum disorder (n = 2,720) who were recruited through a US-based online research database. Parental report of developmental characteristics was assessed through a parent questionnaire, and current autism symptoms were measured via the Social Responsiveness Scale and Social Communication Questionnaire. Multivariate analyses indicated that children with regression had a distinct developmental pattern marked by less delayed early development. However, following regression, these children evinced elevated autism symptom scores and an increased risk for poorer outcomes when compared with the other onset groups.
Journal of autism and developmental disorders, 2010 · doi:10.1007/s10803-010-0998-7