Autism & Developmental

Psychopathology in adults with autism and intellectual disability.

Tsakanikos et al. (2006) · Journal of autism and developmental disorders 2006
★ The Verdict

Autism plus ID does not raise psychiatric risk above ID alone.

✓ Read this if BCBAs serving adults with both autism and intellectual disability in residential or day programs.
✗ Skip if Clinicians who only see high-functioning autistic adults without ID.

01Research in Context

01

What this study did

Tsakanikos et al. (2006) compared psychiatric diagnoses in two groups of adults.

One group had autism plus intellectual disability. The other had intellectual disability alone.

They used medical records and controlled for age, sex, and ability level.

02

What they found

Adults with both autism and ID were no more likely to have any psychiatric diagnosis.

They were actually less likely to receive a personality disorder label.

Autism itself did not add extra psychiatric risk beyond ID.

03

How this fits with other research

Porter et al. (2008) found the same null result in a larger sample, reinforcing the point.

Boudreau et al. (2015) seems to disagree: average-IQ autistic adults had far more psychiatric conditions.

The difference is ID status. Elias studied people with ID; Boudreau et al. (2015) excluded them.

Hand et al. (2020) extends the story to suicidal behavior, showing ID can change risk patterns.

04

Why it matters

Stop assuming every autistic adult is mentally ill. When ID is present, base rates of depression, anxiety, or psychosis match those of other adults with ID. Screen for the same red flags you already know—sleep loss, sudden skill loss, or social withdrawal—and treat what you see, not what you expect.

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Use your usual ID mental-health checklist; skip extra autism-only screens.

02At a glance

Intervention
not applicable
Design
quasi experimental
Sample size
752
Population
autism spectrum disorder, intellectual disability
Finding
null

03Original abstract

There have been few studies of psychopathology in adult with autism. This study examined psychiatric co-morbidity in 147 adults with intellectual disability (ID) and autism and 605 adults with ID but without autism. After controlling for the effects of gender, age, psychotropic medication and level of ID, people with autism and ID were no more likely to receive a psychiatric diagnosis than people with ID only. People with autism were less likely to receive a diagnosis of personality disorder. These findings cast doubts on the hypothesis that adults with ID and autism are more vulnerable to certain psychiatric disorders than non-autistic adults with ID.

Journal of autism and developmental disorders, 2006 · doi:10.1007/s10803-006-0149-3