Autism & Developmental

Minor physical anomalies in childhood autism. Part II. Their relationship to maternal age.

Links (1980) · Journal of autism and developmental disorders 1980
★ The Verdict

Older maternal age links with more minor physical quirks in autistic kids, a handy history-taking cue.

✓ Read this if BCBAs writing developmental histories or teaming with pediatricians.
✗ Skip if Clinicians only handling adult clients with no intake duties.

01Research in Context

01

What this study did

Doctors looked at 45 children with autism. They counted each child’s small body differences, like tiny ear tags or extra skin folds.

They asked moms how old they were when the child was born. Then they checked if older moms had kids with more body differences.

02

What they found

Kids born to older moms had more of these little body quirks. The higher the mom’s age, the more differences showed up.

03

How this fits with other research

Gillberg (1980) saw the same year and same pattern: older moms in their small autism group. The two 1980 studies echo each other.

Whitely et al. (2022) looks opposite at first. They found younger dads, not older ones, tied to autism in later brothers and sisters. But they studied families who already have one autistic child, a very different group. The clash fades once you see the groups differ.

Tioleco et al. (2021) pooled 36 studies and showed mom’s infections while pregnant also nudge autism risk up a bit. Maternal age and infection are both on the long list of prenatal clues.

04

Why it matters

When you take a developmental history, jot down mom’s age at birth and any small physical marks you see. These details don’t diagnose autism, but they add pieces to the puzzle and may guide further medical checks. Sharing this calm fact with parents can also ease self-blame: risk is multi-piece, not one-choice.

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Add ‘maternal age at birth’ and ‘note any small skin tags, ear pits’ to your intake checklist.

02At a glance

Intervention
not applicable
Design
case series
Sample size
45
Population
autism spectrum disorder
Finding
positive

03Original abstract

A group of autistic children have been found to have an excess of minor physical anomalies (MPA) and birth and pregnancy complications. However, there was not a significant positive correlation between the birth and pregnancy complications and the MPA. The relationship between MPA and maternal age in these autistic children was investigated. In the 45 autistic children studied, there was a significant positive correlation between MPA and maternal age at birth. The significance of the relationship between MPA and maternal age deserves further study.

Journal of autism and developmental disorders, 1980 · doi:10.1007/BF02408287