Assessment & Research

Maternal age and infantile autism.

Gillberg (1980) · Journal of autism and developmental disorders 1980
★ The Verdict

Older moms showed up more in early autism cases, but the link flips in high-risk siblings, so age is just one piece of the puzzle.

✓ Read this if BCBAs who take developmental histories or run early-intervention screenings.
✗ Skip if Clinicians only working with adult clients.

01Research in Context

01

What this study did

Gillberg (1980) looked at 20 children with autism. The team wrote down each mother’s age when her baby was born.

They compared these ages to the average mom in the general population.

02

What they found

Mothers of the autistic children were about five years older. The average age was 30.7 years versus 26 in the general group.

Risk went up as mom’s age went up.

03

How this fits with other research

Links (1980) saw the same thing the same year. That group of 45 kids also had older moms.

Whitely et al. (2022) flips the story. In baby brothers and sisters who already have an autistic sibling, younger dads, not older moms, showed higher autism odds. The families in that study were high-risk, so the rule changes.

Tioleco et al. (2021) pooled 36 studies on prenatal risks. Maternal age sits inside that big picture even though infection was the main focus.

04

Why it matters

Older moms are still common in your caseload. Use the age clue when you review developmental history, but do not treat it as a cause. Pair it with other red flags like preterm birth or mid-pregnancy fever. When you work with families who already have one autistic child, shift focus to the infant sibling and watch for early signs no matter what the parents’ ages are.

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Add maternal and paternal age boxes to your intake form and flag any family with an autistic older sibling for closer baby monitoring.

02At a glance

Intervention
not applicable
Design
case series
Sample size
20
Population
autism spectrum disorder
Finding
not reported

03Original abstract

In a total population survey of childhood psychosis in the region of Göteborg, 20 children (2 in every 10,000) fulfilled the diagnostic criteria for infantile autism formulated by Rutter. There was a male preponderance with 15 boys and 5 girls. Eighty-five percent of the mothers were older than average. Mean maternal age in the autistic sample was 30.7 years, compared with 26.0 years in the general population. The difference is statistically significant at the .1% level. There was a strong tendency toward increasing risk of autism in the child with increasing maternal age. The fathers too were much older than average.

Journal of autism and developmental disorders, 1980 · doi:10.1007/BF02408288