Autism & Developmental

Familial heterogeneity in infantile autism.

Baird et al. (1985) · Journal of autism and developmental disorders 1985
★ The Verdict

Autism with severe ID clusters differently in families than higher-functioning autism, so adjust sibling screening and parent education accordingly.

✓ Read this if BCBAs who write intake histories or run parent-training groups in clinic or school settings.
✗ Skip if Practitioners focused solely on single-client skill acquisition with no sibling or family component.

01Research in Context

01

What this study did

Pickering et al. (1985) looked at brothers and sisters of autistic children. They split the families by how severe the child's intellectual disability was. Then they counted how many siblings also had autism or ID. It was a small case-series study, not an experiment.

02

What they found

Siblings of the most severely affected kids had more autism and ID themselves. Siblings of higher-functioning autistic kids had lower rates. The pattern hinted that 'low-IQ autism' and 'higher-IQ autism' may run in families differently.

03

How this fits with other research

Saunders et al. (1988) saw the flip side. They found more Asperger's and bipolar disorder in relatives of high-functioning autistic probands. Together the two papers paint one picture: family risk tracks the proband's ability level.

Chuthapisith et al. (2007) extended the idea to language. Preschool siblings only scored lower on verbal IQ when the autistic child also had ID, echoing the 1985 split.

Johnson et al. (2009) added emotion to the mix. Siblings of autism-plus-ID probands showed more emotional problems than siblings of ID-only probands, strengthening the claim that the double hit creates unique family stress.

04

Why it matters

When you intake a new client, ask about the affected child's IQ range and about sibling development. If the child has severe ID, plan extra screening or support for brothers and sisters. Share the 'different tracks' idea with parents to normalize why one child's autism can feel so different from another's.

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Add one question to your intake form: 'Does the autistic child also have intellectual disability?' Use the answer to flag siblings for closer developmental watch.

02At a glance

Intervention
not applicable
Design
case series
Sample size
29
Population
autism spectrum disorder, intellectual disability
Finding
not reported

03Original abstract

The incidence of autism and cognitive disability was assessed in the biological siblings of 29 autistic probands subdivided on the basis of IQ. A significant clustering of autism and nonspecific intellectual retardation was found in the siblings of severely retarded autistic probands which was not present in the siblings of our higher-functioning autistic sample. These findings suggest that there may be etiological differences in autism, depending on the degree of associated mental retardation.

Journal of autism and developmental disorders, 1985 · doi:10.1007/BF01531501