Autism & Developmental

Effects of Cognitive Behavioral Therapy for Reducing Anxiety in Children with High Functioning ASD: A Systematic Review and Meta-Analysis.

Perihan et al. (2020) · Journal of autism and developmental disorders 2020
★ The Verdict

CBT moderately lowers anxiety in high-functioning kids with autism—make it longer and include parents for the biggest payoff.

✓ Read this if BCBAs serving verbal school-age clients with ASD and anxiety in clinic or school settings.
✗ Skip if Practitioners working with non-verbal or intellectually disabled populations—evidence is still thin here.

01Research in Context

01

What this study did

Celal and colleagues looked at 23 studies that tested CBT for anxiety in children with high-functioning autism. They pooled the numbers to see how well the therapy works. All studies used standard CBT packages, mostly in clinics or schools.

02

What they found

CBT cut anxiety by a moderate amount across the 23 studies. The benefit grew when parents joined the sessions and when treatment lasted longer. Kids who got CBT had noticeably lower worry, avoidance, and physical signs of stress.

03

How this fits with other research

Vause et al. (2020) got even larger drops in obsessive rituals with a CBT plan that starts with a functional behavior assessment. Their single study beat the average effect Celal found for general anxiety.

Byiers et al. (2025) built on Celal’s tip about parent power. They let caregivers pick the top three anxiety problems to target. Caregiver-chosen goals improved faster than in standard CBT.

Pickard et al. (2019) warn that most of the 23 studies Celal pooled were mostly White, higher-income families. The meta-analysis result may not match the diverse kids you see in practice.

Taylor et al. (2017) show CBT can also help children with autism plus intellectual disability when it is blended with behavior support. Celal’s review left these kids out, so the meta result applies only to verbal, higher-IQ learners.

04

Why it matters

You can now tell funders and parents that CBT has a solid evidence base for anxious, verbal learners with ASD. Add a parent module and run at least 12–16 weeks to reach the effect seen in the meta-analysis. Start with a brief functional assessment if rituals are part of the picture; the Tricia study shows this can boost impact.

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Invite parents to sit in on the next CBT session and add two extra weeks to the treatment plan.

02At a glance

Intervention
not applicable
Design
meta analysis
Population
autism spectrum disorder
Finding
positive
Magnitude
medium

03Original abstract

Children with autism spectrum disorder (ASD) are at greater risk for experiencing high levels of anxiety symptoms. Recent evidence suggests Cognitive behavioral therapy (CBT) may also be effective for anxiety reduction in some presentations of ASD. This meta-analysis evaluated twenty-three studies. Results yielded a moderate effect size (g = - 0.66) for the reduction of anxiety symptoms. Moderators indicated larger effects for studies were achieved with parental involvement (g = - 0.85, p < .05) than with child-only treatments (g = - 0.34, p < .05). Short-term interventions generated a smaller effect (g = - 0.37 p < .05) than either standard-term (g = - 1.02, p < .05) or long-term interventions (g = - 0.69, p < .05).Implications for children with ASD are discussed.

Journal of autism and developmental disorders, 2020 · doi:10.1007/s10803-019-03949-7