Autism & Developmental

Early language profiles in infants at high-risk for autism spectrum disorders.

Hudry et al. (2014) · Journal of autism and developmental disorders 2014
★ The Verdict

Losing receptive-word speed by 14 months predicts autism in high-risk infants.

✓ Read this if BCBAs who screen or treat toddlers with an older autistic sibling.
✗ Skip if Practitioners working only with older children or no family history of autism.

01Research in Context

01

What this study did

Hudry et al. (2014) tracked babies who have an older sibling with autism. These infants are 'high-risk' because autism runs in families.

The team checked each baby's understanding of words at 14 months and again at 24 months. They wanted to see which children would later be diagnosed with autism and which would not.

02

What they found

Babies who later got autism started with the same word understanding as other high-risk babies. By 14 months their growth slowed down.

The gap stayed open at 24 months. High-risk babies who did not develop autism caught up to typical levels. The autism group did not catch up.

03

How this fits with other research

Matson et al. (2013) looked at the same high-risk babies and found that higher thinking scores only slightly lowered autism signs. Kristelle's team shows language gives a clearer early red flag than overall IQ.

Reyes et al. (2019) followed similar children into preschool. They found temperament keeps changing in autism, so one-time checks are not enough. Kristelle's data say the same about language: check more than once.

Dembo et al. (2023) used the same math tool—latent profiles—to sort babies with Down syndrome. Both studies prove that babies with the same diagnosis still follow different paths.

04

Why it matters

You can spot likely autism before the second birthday by watching word comprehension, not just how many words a child says. If a high-risk baby loses his early edge by 14 months, start intervention right away instead of waiting for expressive delays to show. Repeat the test at 24 months; do not assume once is enough.

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Track receptive vocabulary every three months for high-risk infants; flag any flattening curve.

02At a glance

Intervention
not applicable
Design
pre post no control
Sample size
104
Population
autism spectrum disorder
Finding
negative
Magnitude
small

03Original abstract

Many preschoolers with autism spectrum disorders (ASD) present relative lack of receptive advantage over concurrent expressive language. Such profile emergence was investigated longitudinally in 54 infants at high-risk (HR) for ASD and 50 low-risk controls, with three language measures taken across four visits (around 7, 14, 24, 38 months). HR infants presented three outcome subgroups: ASD, other atypicality, and typical development. Reduced receptive vocabulary advantage was observed in HR infants by 14 months, but was maintained to 24 months only in ASD/other atypicality outcome subgroups while typically-developing HR infants regained a more normative profile. Few group differences appeared on a direct assessment of language and parent-reported functional communication. Processes of early development toward ASD outcome and in intermediate phenotypes are discussed.

Journal of autism and developmental disorders, 2014 · doi:10.1007/s10803-013-1861-4