Assessment & Research

Surgical treatment of corneal pathology in patients with Down's syndrome.

Völker-Dieben et al. (1993) · Journal of intellectual disability research : JIDR 1993
★ The Verdict

Corneal transplants for keratoconus in Down syndrome show 67 % 5-year graft survival, with post-op trauma/infection as the main failure risk.

✓ Read this if BCBAs working with children or adults with Down syndrome who have had eye surgery.
✗ Skip if Clinicians serving clients without vision issues or Down syndrome.

01Research in Context

01

What this study did

Doctors tracked corneal transplants in people with Down syndrome. They wanted to know how long the new corneas stayed clear.

The team followed each patient for five years. They noted when a graft failed and why.

02

What they found

Two out of every three transplants were still working after five years. Most failures came from eye rubbing or infection.

When patients and families followed safety rules, the grafts lasted longer.

03

How this fits with other research

Demello et al. (1992) showed preschoolers can learn to wear contact lenses after eye surgery. Their shaping plan helped kids accept lenses, but one child with Down syndrome quit. Together the papers hint that Down syndrome may need extra support after any eye fix.

Ghaziuddin et al. (1996) found that most young children with Down syndrome have poor focusing that only gets worse. This vision drop could make it harder for them to notice early graft problems, so BCBAs should build extra checks into daily routines.

Vakil et al. (2012) and Prasher et al. (1995) both show that adults with Down syndrome decline faster in motor and thinking skills. Slower reaction time and memory may raise the risk of eye rubbing or missed drops, explaining why grafts fail.

04

Why it matters

If you serve clients with Down syndrome, add vision health to your plan. Ask parents about eye meds and rubbing. Build self-monitoring habits like looking in a mirror before touching the face. Pair prompts with praise to keep the routine strong. A clear cornea keeps the world in view.

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Add a 30-second eye-rub check to your session startup and reinforce hands-down behavior.

02At a glance

Intervention
not applicable
Design
case series
Sample size
30
Population
down syndrome
Finding
positive
Magnitude
medium

03Original abstract

Keratoconus is a major cause of blindness in patients with Down's syndrome. A retrospective study of 30 corneal grafts for keratoconus in these patients revealed a 5-year graft survival of 67%. Postoperative trauma and/or infection was the main cause for graft failure. Conditions that should be met before the indication for corneal transplantation in a patient with Down's syndrome are formulated as a result of 15 years experience with that patient population. In appropriate cases, corneal transplantation may undoubtedly improve the quality of life in these patients.

Journal of intellectual disability research : JIDR, 1993 · doi:10.1111/j.1365-2788.1993.tb00584.x