Somatic sexual hallucinations and erotomanic delusions in a mentally handicapped woman.
Pimozide erased erotomanic delusions and sexual hallucinations in one older woman with ID, so think psychosis when sexual talk seems bizarre.
01Research in Context
What this study did
Taub et al. (1994) wrote up one older woman with intellectual disability. She kept saying a man loved her and felt sexual touches that were not there. The team gave her Pimozide and watched what happened.
This is a single-case report, not a big trial. Still, it shows how the drug acted in real life.
What they found
The delusions and the fake sexual feelings stopped after Pimozide started. The woman calmed down and no longer talked about the man or the touches.
The paper says the drug worked for as long as she took it.
How this fits with other research
Jones et al. (1992) also gave antipsychotic medicine to an adult with ID, but they saw the scary side effect called neuroleptic malignant syndrome. Both papers are single cases, yet one shows help and the other shows harm. The difference is luck and close nursing watch.
Crosbie (1993) and Chaplin (2009) reviews say most people with both ID and mental illness get too little care. Taub et al. (1994) gives a clear example of what can work when a doctor finally sees the person.
Simpson et al. (2001) looked at crime, not psychosis, in adults with ID. Their big point is that each small study is weak alone. Taub et al. (1994) is useful only as a clue, not as proof for everyone.
Why it matters
If you serve adults with ID, remember that odd sexual talk can be psychosis, not just behavior. Ask for a psych consult and think about Pimozide, but watch for side effects. One calm older woman is not a rule, yet she shows the chance of relief when you treat the illness and not only the behavior.
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02At a glance
03Original abstract
A case of erotic delusion and concurrent somatic sexual hallucination is described in a 66-year-old mentally handicapped woman. The history, mental state and biological investigations convey the impression of erotomania, or de Clerambault's syndrome. Treatment with Pimozide has resulted in a remarkable improvement such that the patient has been symptom free for 8 months at the time of reporting. In the authors' opinion, the case lends support to the argument that erotomania exists as a mono-delusional disorder and is equivalent to the DSM-III-R classification of Paranoid Disorder, Erotomanic Type.
Journal of intellectual disability research : JIDR, 1994 · doi:10.1111/j.1365-2788.1994.tb00351.x