Assessment & Research

Epilepsy and intellectual disability: does epilepsy increase the likelihood of co-morbid psychopathology?

Arshad et al. (2011) · Research in developmental disabilities 2011
★ The Verdict

Among adults with ID sent to mental-health clinics, epilepsy was tied to fewer extra psychiatric diagnoses, not more.

✓ Read this if BCBAs completing intake assessments for adults with dual diagnoses of intellectual disability and epilepsy.
✗ Skip if Clinicians who work only with children or with clients who have no seizure history.

01Research in Context

01

What this study did

Saadia and colleagues looked at mental-health referrals for adults with intellectual disability. They asked: does adding epilepsy raise or lower the chance of extra psychiatric diagnoses?

The team compared two groups already sent to clinics: clients who had both ID and epilepsy, and clients who had ID alone.

02

What they found

Surprise: the epilepsy group carried fewer psychiatric labels, not more. In plain numbers, having seizures was linked to lower odds of additional mental-health diagnoses in the referral pile.

03

How this fits with other research

Lancioni et al. (2011) seems to disagree. That same-year study found adults with ID plus seizures scored higher on a mood checklist. The clash disappears when you see the sampling: Saadia looked at clinic referrals, while E studied residents already living in a facility. Referrals filter out milder cases; facilities house more severe behavior.

Matson et al. (1999) extends the picture. They showed epilepsy plus severe ID predicts weaker social and daily-living skills, even if psychopathology rates stay flat. Together the papers say: expect skill loss, not necessarily more psychiatric labels.

Takano (2022) adds a behavior twist. In profound ID, epilepsy is tied to far more self-injury (two-thirds of cases). So epilepsy may drive specific topographies like self-hits rather than broad psychiatric diagnoses.

04

Why it matters

When an adult with ID and epilepsy lands on your caseload, do not assume a stack of mental-health labels is coming with them. Screen carefully for mood signs and self-injury, but plan interventions around skill-building and safety, not just psychiatric referral counts.

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Pull the last three client files for ID+epilepsy and check if mood or self-injury was screened separately from general psych diagnoses.

02At a glance

Intervention
not applicable
Design
quasi experimental
Sample size
752
Population
intellectual disability
Finding
negative

03Original abstract

Although epilepsy is particularly common among people with intellectual disability (ID) it remains unclear whether it is associated with an increased likelihood of co-morbid psychopathology. We therefore investigated rates of mental health problems and other clinical characteristics in patients with ID and epilepsy (N = 156) as compared to patients with ID but no epilepsy (N = 596). All participants were consecutive referrals to specialist mental heath services. Specialist clinicians agreed on the mental health diagnoses by applying ICD-10 clinical criteria using information gained from interviews with key informants and the patients. Bivariate and multivariate analyses showed that patients with epilepsy were more likely to live in residential housing and have severe ID in line with previous evidence. However, the presence of epilepsy was not associated with an increased likelihood of co-morbid psychopathology. On the contrary, rates of mental health problems, including schizophrenia spectrum, personality and anxiety disorders, were significantly lower among patients with epilepsy. The results are discussed in the context of mood-stabilizing and other psychotropic effects of anti-epileptic drugs in adults with ID and epilepsy, as well as possible diagnostic overshadowing.

Research in developmental disabilities, 2011 · doi:10.1016/j.ridd.2010.10.013