Cognitive and symptom profiles in high-functioning pervasive developmental disorder not otherwise specified and attention-deficit/hyperactivity disorder.
A large WISC-III verbal-block gap plus low CARS-TV social scores helps flag high-functioning ASD over ADHD.
01Research in Context
What this study did
Koyama et al. (2006) compared two groups of bright kids. One group had high-functioning PDD-NOS. The other group had ADHD. Both groups had similar full-scale IQ scores.
The team gave each child the WISC-III IQ test. They also used the CARS-TV to rate autism traits. Then they looked for score patterns that could tell the groups apart.
What they found
The PDD-NOS group scored lower on verbal comprehension. They scored higher on block design, a visuospatial task. The ADHD group did not show this flip.
On the CARS-TV, social-communication items were more severe in the PDD-NOS group. These two clues together helped separate the diagnoses.
How this fits with other research
Cramm et al. (2009) ran a near-copy study with younger kids and found the same WISC-III pattern. Their work is a clean conceptual replication.
Kanai et al. (2017) moved the idea to adults using the WAIS-III. Again, ASD adults showed verbal dips and visuospatial peaks. This extends the finding across the lifespan.
Kim et al. (2020) updated the test to WISC-IV and still saw weaker verbal comprehension in ASD boys. The core pattern has survived test revisions.
Ng et al. (2019) sounds a warning: parent ratings and test scores can disagree. Their data do not cancel the WISC clue, but they remind you to check both sources.
Why it matters
You now have a quick red flag: big gap between WISC-III verbal comprehension and block design plus low social-communication CARS-TV items points toward high-functioning ASD, not ADHD. Use this pattern as one piece of your puzzle, not the whole picture. It can speed up differential diagnosis and guide your next steps, whether that is a full ADOS or an ADHD rating scale.
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Join Free →Pull the verbal comprehension and block-design subtests from the last WISC-III you gave; note any gap ≥9 points and check CARS-TV social items.
02At a glance
03Original abstract
Age- and IQ-balanced 27 children with high-functioning (IQ>or=70) pervasive developmental disorder not otherwise specified (HPDDNOS) and 27 children with attention-deficit/hyperactivity disorder (ADHD) were compared on the Japanese version of Wechsler Intelligence Scale for Children Third Edition (WISC-III) and the Childhood Autism Rating Scale-Tokyo Version (CARS-TV). Compared with the ADHD children, the HPDDNOS children scored significantly lower on verbal comprehension, vocabulary, and comprehension, but significantly higher on block design. After controlling for the total CARS-TV score, the HPDDNOS children were significantly more abnormal on "relationships with people," "nonverbal communication," and "general impressions," but less abnormal on "near receptor responsiveness" and "activity level." These differences in cognitive and autistic symptom profiles may help professionals to distinguish clinically between both conditions.
Journal of autism and developmental disorders, 2006 · doi:10.1007/s10803-006-0075-4