Assessment & Research

Cognitive and symptom profiles in high-functioning pervasive developmental disorder not otherwise specified and attention-deficit/hyperactivity disorder.

Koyama et al. (2006) · Journal of autism and developmental disorders 2006
★ The Verdict

A large WISC-III verbal-block gap plus low CARS-TV social scores helps flag high-functioning ASD over ADHD.

✓ Read this if BCBAs doing assessments with school-age kids who have unclear ASD or ADHD pictures.
✗ Skip if Clinicians working only with adults or with kids who already have clear diagnoses.

01Research in Context

01

What this study did

Koyama et al. (2006) compared two groups of bright kids. One group had high-functioning PDD-NOS. The other group had ADHD. Both groups had similar full-scale IQ scores.

The team gave each child the WISC-III IQ test. They also used the CARS-TV to rate autism traits. Then they looked for score patterns that could tell the groups apart.

02

What they found

The PDD-NOS group scored lower on verbal comprehension. They scored higher on block design, a visuospatial task. The ADHD group did not show this flip.

On the CARS-TV, social-communication items were more severe in the PDD-NOS group. These two clues together helped separate the diagnoses.

03

How this fits with other research

Cramm et al. (2009) ran a near-copy study with younger kids and found the same WISC-III pattern. Their work is a clean conceptual replication.

Kanai et al. (2017) moved the idea to adults using the WAIS-III. Again, ASD adults showed verbal dips and visuospatial peaks. This extends the finding across the lifespan.

Kim et al. (2020) updated the test to WISC-IV and still saw weaker verbal comprehension in ASD boys. The core pattern has survived test revisions.

Ng et al. (2019) sounds a warning: parent ratings and test scores can disagree. Their data do not cancel the WISC clue, but they remind you to check both sources.

04

Why it matters

You now have a quick red flag: big gap between WISC-III verbal comprehension and block design plus low social-communication CARS-TV items points toward high-functioning ASD, not ADHD. Use this pattern as one piece of your puzzle, not the whole picture. It can speed up differential diagnosis and guide your next steps, whether that is a full ADOS or an ADHD rating scale.

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→ Action — try this Monday

Pull the verbal comprehension and block-design subtests from the last WISC-III you gave; note any gap ≥9 points and check CARS-TV social items.

02At a glance

Intervention
not applicable
Design
quasi experimental
Sample size
54
Population
autism spectrum disorder, adhd
Finding
not reported

03Original abstract

Age- and IQ-balanced 27 children with high-functioning (IQ>or=70) pervasive developmental disorder not otherwise specified (HPDDNOS) and 27 children with attention-deficit/hyperactivity disorder (ADHD) were compared on the Japanese version of Wechsler Intelligence Scale for Children Third Edition (WISC-III) and the Childhood Autism Rating Scale-Tokyo Version (CARS-TV). Compared with the ADHD children, the HPDDNOS children scored significantly lower on verbal comprehension, vocabulary, and comprehension, but significantly higher on block design. After controlling for the total CARS-TV score, the HPDDNOS children were significantly more abnormal on "relationships with people," "nonverbal communication," and "general impressions," but less abnormal on "near receptor responsiveness" and "activity level." These differences in cognitive and autistic symptom profiles may help professionals to distinguish clinically between both conditions.

Journal of autism and developmental disorders, 2006 · doi:10.1007/s10803-006-0075-4