Assessment & Research

Clinical characteristics of children with ASD and comorbid ADHD: Association with social impairment and externalizing and internalizing behaviours.

Dellapiazza et al. (2021) · Research in developmental disabilities 2021
★ The Verdict

Kids with both ASD and ADHD show extra social hurt; treat the ADHD part for acting-out and the ASD part for withdrawal.

✓ Read this if BCBAs doing assessments or writing BSPs for school-age kids with dual diagnoses.
✗ Skip if Clinicians who only serve single-diagnosis or adult populations.

01Research in Context

01

What this study did

Dellapiazza et al. (2021) compared three groups of school-age kids: ASD plus ADHD, ADHD only, and neurotypical peers.

They used rating scales and interviews to map social skills, acting-out behaviors, and internalizing problems like worry or withdrawal.

The goal was to see if the combo group looked different from the single-diagnosis kids.

02

What they found

The ASD+ADHD group showed the worst social impairment, worse than ADHD-only and typical peers.

Acting-out tracked with how severe the ADHD symptoms were, while withdrawn or anxious moods tracked with ASD severity.

In short, each diagnosis kept its own “signature” problems, and together they piled up.

03

How this fits with other research

Ohan et al. (2015) already showed that kids with both conditions score lower on daily living and social skills; Florine extends that by showing which diagnosis drives which problem.

McIntyre et al. (2017) found that even ADHD symptoms (not full diagnosis) worsen social scores in ASD; Florine confirms and sharpens the picture using full diagnoses and parent reports.

Rosello et al. (2022) pooled 34 studies and reached the same bottom line—more impairment when ASD and ADHD meet—so Florine’s 2021 data sit right inside that bigger wave.

Crisci et al. (2026) will add a twist: half of each single-diagnosis group actually share the same “social deficits plus behavior dysregulation” profile, reminding us to look at the child, not just the label.

04

Why it matters

When a child carries both ASD and ADHD, expect social struggles above the ADHD-only level, and know that acting-out usually comes from ADHD severity while mood withdrawal comes from ASD severity. Tailor your plan: teach social skills, but also target self-control or anxiety depending on which driver is louder that day.

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Pull your client’s last rating scales: if externalizing is high, add a self-management or attention break plan; if internalizing is high, add social narratives or coping scripts.

02At a glance

Intervention
not applicable
Design
quasi experimental
Sample size
186
Population
autism spectrum disorder, adhd, neurotypical
Finding
not reported

03Original abstract

BACKGROUND: Autism spectrum disorder (ASD) and attention-deficit hyperactivity disorder (ADHD) are frequently occurring conditions that are often associated (ASD + ADHD). However, there are few comparative studies concerning the clinical presentation in patients formally diagnosed with both ASD and ADHD. Here, we aimed to 1) compare social impairment and externalizing/internalizing behavioural problems across four groups of children: ASD + ADHD, ASD alone, ADHD alone, and typical development and 2) examine their bidirectional relationship with ASD and/or ADHD symptoms. METHODS: This study included 186 participants from 6 to 12 years of age: single ASD (n = 98), ASD + ADHD (n = 29), single ADHD (n = 28), and TD (n = 31). RESULTS: The results showed that children in the ASD + ADHD and single ASD groups had a higher level of social impairment than those in the single ADHD group. In addition, children in the single ADHD group presented a greater attention deficit than those in the single ASD group. Externalizing /internalizing behaviours were more frequent in all groups with neuro-developmental disorders than in typical development. In addition, externalizing behavioural problems were related to ADHD severity in the ASD + ADHD and single ADHD groups, whereas internalizing behaviours were related to ASD severity. CONCLUSIONS: These findings highlight the specific needs of children who have both ASD and ADHD and underscore the necessity of individualizing their interventions.

Research in developmental disabilities, 2021 · doi:10.1016/j.ridd.2021.103930