Brief report: autistic traits in twins vs. non-twins--a preliminary study.
Twin boys earn slightly higher parent-reported autistic-trait scores, so interpret borderline SRS results with family context in mind.
01Research in Context
What this study did
Parents filled out the Social Responsiveness Scale for twin boys and girls and for boys and girls who were not twins.
The team then compared the scores to see if twin status changed how many mild autistic traits were reported.
What they found
Twin boys earned slightly higher SRS scores than non-twin boys, hinting at more sub-threshold autistic traits.
Twin girls scored the same as non-twin girls, so the effect was limited to males.
How this fits with other research
Isaksson et al. (2019) used a co-twin control method and showed that, once family factors are held constant, the link between autistic traits and poor mind-reading disappears. This suggests the slightly elevated SRS scores in Alexander’s twin boys may reflect shared family genetics or environment rather than a true trait spike.
Kupzyk et al. (2011) tracked almost four hundred twin pairs and found clumsiness and autistic traits share roughly two-thirds of their genetic influences, giving a concrete mechanism for why twins—who share DNA—might score a bit higher.
Zubizarreta et al. (2025) also ran a within-twin analysis and saw camouflaging stress effects vanish after family controls, echoing the same “check the family context” warning.
Why it matters
When you see a boy twin hover near the SRS cutoff, remember the score might be nudged up by shared family liability rather than a clinical concern. Re-test, gather developmental history, and compare with co-twin performance before labeling or referring. Use the same caution when twins join social-skills groups; their “autistic” score could be a family echo, not a treatment need.
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02At a glance
03Original abstract
Previous studies have suggested that among affected sib pairs with autism there is an increase in the frequency of twins over what would be expected in comparison to the prevalence of twins in the general population. In this study we sought to determine whether sub-threshold autistic traits were more pronounced in twins than in non-twins. The Social Responsiveness Scale (SRS) was administered in an epidemiologic twin sample (n=802) and in a separate population-based sample of non-twins ascertained from a local school district (n=255). For males (but not females), the mean SRS score was significantly higher among twins than among non-twins. As has been suggested for autism, twin status may incur increased liability to subthreshold autistic symptomatology, particularly in males.
Journal of autism and developmental disorders, 2005 · doi:10.1007/s10803-004-1040-8