Brief report: autism in individuals with Down syndrome.
Autism tests can disagree in Down syndrome—keep testing and look at real-life behavior.
01Research in Context
What this study did
The team looked at 13 people with Down syndrome. They gave each person two autism tests. One test was a parent interview. The other test watched the person play and talk.
They wanted to see if both tests would give the same answer.
What they found
Five people showed some autism traits. But the tests did not agree. Some people passed the interview yet failed the play test. Others failed the interview yet passed the play test.
No clear yes-or-no answer came out.
How this fits with other research
Lord et al. (1997) showed the interview works well in other groups. Their work gave the tool that M et al. later tried in Down syndrome.
Ventola et al. (2007) also saw mixed agreement. They compared autism tests in toddlers with general delays. Like M et al., they found one test can say yes while another says no.
Glenn et al. (2013) tweaked a mood quiz for adults with Down syndrome. They also saw low sensitivity. The pattern is the same: standard tools need extra care in this population.
Why it matters
If you assess a child with Down syndrome, do not stop after one test. Use both interview and observation. When scores clash, gather more data. Watch the child at school and home. Ask the team what they see. A single test can miss or over-call autism in this group.
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02At a glance
03Original abstract
As an off-shoot of a study examining the reliability and validity of an adapted version of the Pre-Linguistic Autism Diagnostic Observation Schedule (A-PL-ADOS), 13 individuals with Down syndrome with IQs ranging between 24 and 48 were administered the Autism Diagnostic Interview-Revised (ADI-R) and the A-PL-ADOS, which are well-validated interview and observational diagnostic measures. Three out of 13 met lifetime criteria on the ADI-R, but none of these three showed behavior that met the criterion for autism on the A-PL-ADOS (although two nearly did so). However, two individuals did meet the A-PL-ADOS criterion and showed behavior that fell only just short of meeting lifetime criteria on the ADI-R. Altogether, 5 individuals with Down syndrome may be considered to show an autism spectrum disorder. Of the remaining 8, some showed a few autistic features, and some showed none. The findings raise both methodological and conceptual issues.
Journal of autism and developmental disorders, 2005 · doi:10.1007/s10803-005-0010-0