Assessment & Research

Anxiety and Depression in Bidirectional Relations Between Pain and Smoking: Implications for Smoking Cessation.

Zale et al. (2016) · Behavior modification 2016
★ The Verdict

Anxiety and depression glue the pain-smoking cycle together—treat mood to protect quit attempts.

✓ Read this if BCBAs running smoking-cessation programs for adults who report chronic pain.
✗ Skip if Practitioners who work solely with children or non-smoking populations.

01Research in Context

01

What this study did

Tonnsen et al. (2016) wrote a narrative review. They pulled together studies on pain, smoking, anxiety, and depression.

The authors asked: do anxiety and depression act as middle-men that keep the pain-smoking loop alive and make quitting harder?

02

What they found

The review says pain can fuel smoking, and smoking can worsen pain. Anxiety and depression sit in the middle of this two-way street.

When people try to quit, pain can spike. If anxiety or depression are high, the pain spike can push them back to cigarettes.

03

How this fits with other research

Pielech et al. (2016) give you a quick tool: the 2-item Values Tracker. It adds extra punch beyond pain scores when you track how clients function day-to-day. You can pair it with mood checks to see if valued action drops when anxiety rises.

Andersen et al. (2023) show the same mediator idea in autism. Teen anxiety and depression fully explain why an early autism diagnosis predicts lower quality of life at age 22. The pattern matches L et al.: internalizing problems bridge physical or neuro-difference to life outcomes.

Lee et al. (2023) swap the mediator. In youth with ADHD, self-stigma—not anxiety—links heavy social-media use to distress. The lesson: pick the mediator that fits your client group. Pain-smoking loop? Target anxiety and depression. Social-media loop? Target stigma.

04

Why it matters

If you treat tobacco dependence, always screen for anxiety and depression, especially when your client reports chronic pain. Add a brief values measure like Melissa et al.’s tracker each session. When pain flares after quitting, teach coping skills for mood first; that may keep the cigarette off-limits.

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Add one anxiety and one depression question to your intake form; track the answers weekly during quit attempts.

02At a glance

Intervention
not applicable
Design
narrative review
Population
substance use disorder
Finding
not reported

03Original abstract

Pain and tobacco smoking are highly prevalent and comorbid conditions that impose considerable burdens on individuals and health care systems. A recently proposed reciprocal model suggests that these conditions interact in a bidirectional manner, resulting in greater pain and the maintenance of tobacco addiction. Anxiety and depression are common among smokers in pain and have been identified as central mechanisms of interest. There is emerging evidence that smokers with anxiety/depression may experience more severe pain and functional impairment, greater pain-induced motivation to smoke, and increased sensitivity to pain during periods of smoking abstinence. Based on empirical findings, we hypothesize that these experiences may engender expectations that abstaining from smoking will exacerbate both pain and negative affect, thus eroding self-efficacy for smoking cessation and increasing perceived barriers to quitting. The goal of this narrative review is to examine the role of anxiety/depression in complex pain-smoking relations so as to advance evolving theoretical perspectives and inform the development of tailored interventions.

Behavior modification, 2016 · doi:10.1177/0145445515610744