Assessment & Research

Abnormal selective attention normalizes P3 amplitudes in PDD.

Hoeksma et al. (2006) · Journal of autism and developmental disorders 2006
★ The Verdict

In adolescents with PDD, atypical selective-attention brain activity may paradoxically normalize later ERP responses, highlighting age-sensitive neural compensation.

✓ Read this if BCBAs running EEG or auditory attention assessments with autistic teens.
✗ Skip if Practitioners who work only with preschoolers and do not use brain-wave tools.

01Research in Context

01

What this study did

Giallo et al. (2006) compared brain waves in kids and teens with pervasive developmental disorder (PDD) to typically developing peers.

They measured the P3 wave, a spike that shows the brain just noticed something important.

All children sat quietly while odd tones popped up among regular tones.

02

What they found

Younger children with PDD had smaller P3 spikes than controls.

Surprisingly, adolescents with PDD showed normal-sized P3 spikes.

Their earlier selective-attention waves looked odd, hinting the teens used a different brain route to reach the same endpoint.

03

How this fits with other research

Anthony et al. (2020) saw smaller early brain waves in ASD children, seeming to clash with the teen normalization here. The gap is age: early sensory gaps may close or be patched by attention tricks as kids grow.

Chien et al. (2018) later found shorter P3a timing in older youth with ASD, extending this idea that the P3 family keeps changing with age.

Zigler et al. (1989) first reported smaller P3b in autism, giving a baseline that shows the 2006 teen data as a possible developmental update, not a fixed deficit.

04

Why it matters

If you test teens with ASD, a "normal" P3 does not guarantee typical processing. Ask yourself what compensatory path they took. Pair brain checks with real-world attention probes. Track the same client over years; an early flat P3 can bloom later, guiding when to boost or fade supports.

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Add a simple auditory oddball game to your teen session: watch if reaction time, not just accuracy, changes as tasks get harder.

02At a glance

Intervention
not applicable
Design
case control
Population
autism spectrum disorder
Finding
mixed

03Original abstract

This paper studied whether abnormal P3 amplitudes in PDD are a corollary of abnormalities in ERP components related to selective attention in visual and auditory tasks. Furthermore, this study sought to clarify possible age differences in such abnormalities. Children with PDD showed smaller P3 amplitudes than controls, but no abnormalities in selective attention. Adolescents with PDD showed abnormal selective attention, as reflected by larger auditory Processing Negativity (PN) and visual N2b, but no P3 abnormalities. Dipole localizations revealed that the locations of PN generators in subjects with PDD differed from controls. It was concluded that the abnormalities in selective attention in adolescents with PDD have a normalizing effect on P3, and possibly act as a compensatory process.

Journal of autism and developmental disorders, 2006 · doi:10.1007/s10803-006-0102-5