Autism & Developmental

Temperament in the first 2 years of life in infants at high-risk for autism spectrum disorders.

Clifford et al. (2013) · Journal of autism and developmental disorders 2013
★ The Verdict

Parent-rated baby temperament spots autism risk: watch for sensory overload and low cuddliness after 12 months.

✓ Read this if BCBAs who screen babies with autistic older siblings.
✗ Skip if Clinicians working only with verbal school-age clients.

01Research in Context

01

What this study did

Researchers asked parents to rate the temperament of babies who have an older sibling with autism.

These high-risk infants were tracked from 6 to 24 months.

The team wanted to see if early temperament traits predict later autism diagnosis.

02

What they found

High-risk babies showed less Surgency and Effortful Control.

The babies later diagnosed with autism were extra sensitive to sights and sounds.

They also showed more negative mood and were harder to cuddle after 12 months.

03

How this fits with other research

Beck et al. (2021) extends this work by showing the FYI 2.0 screener also picks up social-communication and sensory quirks at 12 months.

Hatton et al. (2004) came first and proved autism can be reliably diagnosed by age 2, so the temperament flags line up with stable early diagnosis.

Baker et al. (2025) look at rapid eye-movement deficits in parents and kids, hinting that different biological markers may sit in the same families.

04

Why it matters

You can watch for two parent-noticed red flags after the first birthday: high perceptual sensitivity and low cuddliness.

Add the free FYI 2.0 items to your intake to catch the same traits with a checklist.

Spotting these signs early lets you start routines that reduce sensory overload and build joint attention before autism is formally diagnosed.

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Add the FYI 2.0 sensory-regulatory items to your parent interview for any baby sibling of a child with autism.

02At a glance

Intervention
not applicable
Design
case control
Sample size
104
Population
autism spectrum disorder
Finding
mixed

03Original abstract

The current study investigated early temperament in 54 infants at familial high-risk of ASD and 50 controls. Parental report of temperament was assessed around 7, 14 and 24 months of age and diagnostic assessment was conducted at 3 years. The high-risk group showed reduced Surgency at 7 and 14 months and reduced Effortful Control at 14 and 24 months, compared to controls. High-risk infants later diagnosed with ASD were distinguished from controls by a temperament profile marked by increased Perceptual Sensitivity from the first year of life, and increased Negative Affect and reduced Cuddliness in the second year of life. Temperament may be an important construct for understanding the early infant development of ASD.

Journal of autism and developmental disorders, 2013 · doi:10.1007/s10803-012-1612-y