Autism & Developmental

Psychiatric comorbidity in young adults with a clinical diagnosis of Asperger syndrome.

Lugnegård et al. (2011) · Research in developmental disabilities 2011
★ The Verdict

Most young adults with Asperger syndrome already carry depression or anxiety, so screen and refer early.

✓ Read this if BCBAs working with adults or teens who have an Asperger diagnosis.
✗ Skip if Practitioners focused only on early-childhood or non-autistic populations.

01Research in Context

01

What this study did

Lugnegård et al. (2011) looked at 54 young adults who carried an Asperger diagnosis.

A clinician interviewed each person and checked records for any past or current mental-health condition.

The team simply counted how many met criteria for depression, anxiety, or other psychiatric disorders.

02

What they found

Seven out of ten had lived through at least one major depressive episode.

Half also met criteria for an anxiety disorder such as social phobia or panic.

The numbers show that extra mental-health problems are the rule, not the exception, in this group.

03

How this fits with other research

Chien et al. (2021) tracked a whole nation and found the same pattern: depression risk stays high in adults with Asperger profiles, especially women.

Supekar et al. (2017) show the picture changes with age—depression and schizophrenia rise after young adulthood while ADHD and epilepsy fade—so Tove’s snapshot fits the early part of that curve.

Laugeson et al. (2014) give hope: CBT can cut anxiety in autistic youth, suggesting that screening followed by talk therapy may lower the heavy load Tove saw.

Ben Hassen et al. (2023) hint at why the load is so high—adults with ASD struggle to name and feel emotions—so untreated alexithymia may feed the depression numbers.

04

Why it matters

If you serve adults with an Asperger diagnosis, always add brief depression and anxiety screens to your intake.

Early flags let you refer for CBT, adjust goals when mood is low, and track whether your behavioral plan is helping the whole person, not just their social skills.

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Add two quick questions to intake: “Have you felt down most days for two weeks?” and “Do you worry so much it gets in your way?”—then note yes answers for referral.

02At a glance

Intervention
not applicable
Design
case series
Sample size
54
Population
autism spectrum disorder
Finding
not reported

03Original abstract

In children with autism spectrum disorders, previous studies have shown high rates of psychiatric comorbidity. To date, studies on adults have been scarce. The aim of the present study was to investigate psychiatric comorbidity in young adults with Asperger syndrome. Participants were 26 men and 28 women (mean age 27 years) with a clinical diagnosis of Asperger syndrome. Psychiatric comorbidity was assessed by the Structured Clinical Interview for DSM-IV Axis I Disorders. IQ was measured using the Wechsler Adult Intelligence Scale, Third Edition. Autism spectrum diagnoses were confirmed using the DIagnostic Interview for Social and Communication Disorders. In our study group, 70% had experienced at least one episode of major depression, and 50% had suffered from recurrent depressive episodes. Anxiety disorders were seen in about 50%. Psychotic disorders and substance-induced disorders were uncommon. In conclusion, young adults with autism spectrum disorders are at high risk for mood and anxiety disorders. To identify these conditions and offer treatment, elevated vigilance is needed in clinical practice.

Research in developmental disabilities, 2011 · doi:10.1016/j.ridd.2011.03.025