Autism & Developmental

Preemptive interventions for infants and toddlers with a high likelihood for autism: A systematic review and meta-analysis.

Hampton et al. (2022) · Autism : the international journal of research and practice 2022
★ The Verdict

Parent coaching for babies at high autism risk always teaches parents, yet kids only blossom when parents actually nail the strategies every day.

✓ Read this if BCBAs running early-intervention or Part C programs for infants and toddlers.
✗ Skip if Clinicians who only serve school-age kids or use strictly clinician-delivered therapy.

01Research in Context

01

What this study did

Whiteside et al. (2022) looked at every trial that coached parents of babies who had a high chance of later autism. They wanted to know if teaching parents early helps kids grow better.

The team pulled together all parent-training studies for infants and toddlers. Then they ran a meta-analysis to see if the coaching really moved child skills.

02

What they found

Parents learned the strategies every time. Their ratings went up like clockwork.

Child gains were hit-or-miss. When parents used the moves well, kids made progress. When parents drifted, scores stayed flat.

03

How this fits with other research

Klusek et al. (2022) shows the same pattern in the real world. In a big community roll-out of the Social ABCs, toddlers only improved when parents kept the techniques alive at home.

Rouhandeh et al. (2022) squeezed the same idea into just four weeks. Brief coaching still lifted both parent skill and child social talk, backing the claim that parent use is the key lever.

Byiers et al. (2025) widens the lens. Their map of 69 baby studies says behavioral work is booming for 0-2 year olds, but most trials skip the parent-implementation check. H et al. fills that gap by showing quality beats quantity.

04

Why it matters

You can start parent coaching before a firm autism diagnosis. Teach a few clear moves, then watch the parent, not just the child. If mom or dad drifts, pause and retrain before adding new goals. Quick parent fidelity checks each visit tell you whether the child gains will stick.

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Add a two-minute parent fidelity probe to each session and re-teach on the spot if scores dip below 80%.

02At a glance

Intervention
parent training
Design
systematic review
Population
autism spectrum disorder
Finding
mixed

03Original abstract

Interventions to address core symptoms for young children on the autism spectrum have a strong and growing evidence base. Adapting and delivering evidence-based interventions to infants and toddlers with a high likelihood for autism is a logical next step. This systematic review and meta-analysis summarize the association between infant and toddler interventions and developmental and family outcomes. Results indicate that these early interventions are effective for improving parent implementation of core strategies, yet the effects do not readily translate to child outcomes. However, key studies demonstrate conditional results that indicate that parent implementation is associated with child outcome. Implications for research and practice toward building adaptive interventions that respond to parent implementation and changing child characteristics are discussed.

Autism : the international journal of research and practice, 2022 · doi:10.1177/13623613211050433