Autism & Developmental

Imitation in fragile X syndrome. Implications for autism.

Macedoni-Luksic et al. (2009) · Autism : the international journal of research and practice 2009
★ The Verdict

In kids with fragile X, extra groping movements during imitation can flag co-occurring autism better than simple accuracy scores.

✓ Read this if BCBAs assessing or treating children with fragile X syndrome in clinic or school settings.
✗ Skip if Practitioners who work only with idiopathic autism and no FXS cases.

01Research in Context

01

What this study did

Macedoni-Luksic et al. (2009) watched kids with fragile X syndrome copy hand and finger movements. Some kids also had autism. The team scored how close each copy was to the model.

They looked at two groups: FXS only and FXS plus autism. Both groups tried the same imitation tasks in a quiet lab room.

02

What they found

Both groups got about the same number of moves right. Accuracy alone did not separate the kids.

The big clue was extra motion. Kids with FXS plus autism showed more groping and wandering hand paths. These extra moves were the red flag.

03

How this fits with other research

Du et al. (2024) saw lower imitation accuracy in autistic kids without FXS. Marta saw equal accuracy in FXS kids with autism. The difference is the group: Bang studied idiopathic autism; Marta studied autism tied to FXS. Same word "autism," different bodies.

Demily et al. (2018) also found good accuracy in intellectually able adults with ASD, but those adults still moved awkwardly when planning their own actions. Marta’s kids looked similar: right final form, messy path.

Thurman et al. (2015) later mapped how autism traits grow differently in FXS across time. Marta’s 2009 focus on groping fits that slower, bumpier developmental track.

04

Why it matters

When you test imitation in kids with FXS, ignore the old rule of counting only right or wrong. Watch for extra wiggles, finger taps, or hand loops. Those movement errors can signal autism layered on FXS and guide you to add motor planning support, not just more imitation drills.

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→ Action — try this Monday

During your next imitation probe, score both accuracy and any extra hand motions; note groping as a separate data column.

02At a glance

Intervention
not applicable
Design
quasi experimental
Sample size
22
Population
autism spectrum disorder, mixed clinical
Finding
mixed

03Original abstract

To address the specific impairment of imitation in autism, the imitation abilities of 22 children with fragile X syndrome (FXS) with and without autism were compared. Based on previous research, we predicted that children with FXS and autism would have significantly more difficulty with non-meaningful imitation tasks. After controlling for full-scale IQ and age, the groups did not differ in their overall imitation accuracy scores, but analysis of error patterns revealed that children with FXS and autism made more groping errors and additional movements than the comparison group. These error patterns are consistent with the hypothesis that an action production system deficit plays an important role in the overall imitation deficit in autism, at least in children with FXS.

Autism : the international journal of research and practice, 2009 · doi:10.1177/1362361309337850