Autism & Developmental

Hemispheric asymmetries and early infantile autism.

McCann (1981) · Journal of autism and developmental disorders 1981
★ The Verdict

Left-brain damage is too simple an answer for autism language woes.

✓ Read this if BCBAs who assess language in autistic learners of any age.
✗ Skip if Clinicians only working with acquired adult aphasia.

01Research in Context

01

What this study did

The author read every paper he could find on brain sides and autism. He asked: does damage to the left side explain the language problems we see?

He looked at handedness reports, brain scans, and autopsy work. The review covered kids with early infantile autism.

02

What they found

No. A simple left-brain injury story does not fit the data. Language trouble in autism needs a more careful explanation.

The old idea that all autistic kids are left-side broken was too neat.

03

How this fits with other research

Blanchard et al. (1979) came first. They saw more right-wider-than-left back-brain asymmetry in autistic kids and blamed left-side faults. McCann (1981) used their case series as a foil and said the picture is messier.

Faso et al. (2016) later pooled imaging data and moved the field forward. They showed right-side language patches pop up only when the task is hard. Their meta-analysis replaces the old guess-work with numbers.

Rysstad et al. (2016) also extended the story. They counted hands and proved non-right-handedness really is more common in autism, something the 1981 review doubted as crude evidence.

04

Why it matters

Do not assume one broken side causes language delay in autism. Use current imaging or at least check both hands. When you see mixed dominance, plan teaching that taps both sides: visual cues, gestures, and spoken words together. Keep watching new brain-coupling studies; they are already shaping early biomarkers and targeted language plans.

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Screen handedness at intake and pair spoken targets with visual cues for non-right-handed kids.

02At a glance

Intervention
not applicable
Design
narrative review
Population
autism spectrum disorder
Finding
not reported

03Original abstract

The observation that language disorders constitute a major symptom of early infantile autism has led some researchers to speculate that the autistic syndrome may be a result of brain damage to the left hemisphere. Such speculation has fostered a number of studies in which attempts have been made to link autism with ostensibly positive signs of left hemisphere damage, such as left-handedness and preferences for "right hemisphere" functional and cognitive activities. In the present review, contributions to this area are systematically reviewed. Studies attempting to demonstrate that an unusually high incidence of left-handedness occurs in autistic samples are examined. Functional and morphological studies examining patterns of asymmetry in autistic samples are reviewed. It is shown that most studies on handedness fail to account adequately for the role that age of subjects may play in the manifestation of left-handedness. A simple cause-and-effect model of abnormal cerebral asymmetry and autism is rejected in favor of a more integrative yet parsimonious model that specifically attempts to explain the language disorder common to autism.

Journal of autism and developmental disorders, 1981 · doi:10.1007/BF01531615