Executive functioning in autism spectrum disorders: a gender comparison of response inhibition.
On the stop-task, only girls with autism show a response-inhibition deficit — boys with autism perform like typical peers.
01Research in Context
What this study did
Researchers gave a stop-signal task to adolescents with autism and typical peers. They split each group by sex to see who pressed slower when told to hold back. The task measures response inhibition — the split-second brake you use to stop an action.
What they found
Only girls with autism hit the brake more slowly than all other groups. Boys with autism stopped just as fast as typical boys. The female-only lag shows inhibition is not a blanket autism problem — sex matters.
How this fits with other research
Dall et al. (1997) once found no inhibition deficit in autism at all. Their sample mixed boys and girls, so the girl-specific lag was hidden. Amore et al. (2011) uncovers the sex split, solving the old puzzle.
Morrison et al. (2017) later asked parents to rate daily executive skills. Parents also scored girls with autism lower than boys, even when core autism traits were equal. The lab task and home ratings now agree: real-life inhibition is tougher for girls.
Padmanabhan et al. (2015) tracked inhibition across age. Kids with autism did not get faster as they grew, while typical kids did. The 2011 girl deficit fits inside this flat trajectory — adolescent girls still sit at the slow end.
Why it matters
When you test inhibition, check sex first. A boy who stops on time may still need help elsewhere, while a girl who looks similar on social scores may secretly struggle with impulse control. Add girl-specific inhibition goals to her plan — shorter work periods, extra pause cues, or self-monitoring scripts. Share the data with parents so they expect homework meltdowns stem from a brake problem, not defiance.
Want CEUs on This Topic?
The ABA Clubhouse has 60+ free CEUs — live every Wednesday. Ethics, supervision & clinical topics.
Join Free →Run a five-trial stop-signal probe with your female clients; if lag appears, add brief pause-and-check intervals to their DTT or homework routine.
02At a glance
03Original abstract
Although autism spectrum disorders (ASD) affect more males than females, it is not clear whether neurobehavioural correlates of ASD are equivalent across genders. This study examined gender differences in neurobehavioural functioning in boys and girls with ASD. Participants were males with ASD (n = 10), females with ASD (n = 13), typically developing males (n = 8), and typically developing females (n = 14). Each completed the stop task, a common measure of response inhibition. Females with ASD demonstrated a significant increase in stopping time (indicating poorer inhibition). By contrast, no response inhibition impairments were evident among males with ASD. Females with ASD may have a different neurobehavioural profile, and therefore different clinical needs, when compared with males with ASD.
Journal of autism and developmental disorders, 2011 · doi:10.1007/s10803-010-1039-2