Endometrial adenocarcinoma presenting in a premenopausal patient with tuberous sclerosis.

Doctors wrote up one patient. She was 39, had tuberous sclerosis, and severe intellectual disability.

She went to the hospital with belly pain. Tests showed endometrial adenocarcinoma, a cancer of the uterus lining.

The paper simply tells her medical story. No behavior program, no ABA data.

The team found that uterine cancer can show up early in women with tuberous sclerosis.

They urged gynecologists to watch for this rare but serious match-up.

Hilton et al. (2010) also push genetic screening, but for a different gene. They say order PTEN tests when you see big-head ASD or developmental delay.

Thomas et al. (2021) and Mammarella et al. (2022) echo the same tune: run modern gene tests on anyone with unexplained delays.

All four papers differ in the exact gene or cancer risk, yet they agree on one point. Dig deeper than the behavior plan; look for hidden medical causes.

You probably won’t treat uterine cancer, but you do spend hours with clients. Note odd pain, bleeding, or fatigue in women with tuberous sclerosis and flag the medical team. Quick referrals can save lives.