Coincidence of Tourette's disorder and infantile autism.
Autism and Tourette’s can ride together even without drugs, so watch for tics and plan care for both.
01Research in Context
What this study did
Doctors wrote up one boy who had both autism and Tourette’s.
They checked his norepinephrine level to see if it differed from kids with only one disorder.
No pills caused the tics, so the team ruled out drug side-effects.
What they found
The boy truly had both conditions at the same time.
His chemical profile hinted that norepinephrine might mark the overlap.
How this fits with other research
Lim et al. (2016) later tested many kids and showed the double diagnosis is real, not a one-off.
Rutter et al. (1987) ran a bigger study on catecholamines in autism only; their mixed results warn us the marker is still fuzzy.
Steiner et al. (2004) and Matson et al. (2004) used the same single-case style to link autism with other medical issues, showing this method keeps spotting rare combos.
Why it matters
If a client has autism plus new tics, think beyond medication effects. Track tics, note family history, and consider a medical referral. One case may not give a clear biomarker, but it tells us to keep looking and to treat each condition separately.
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02At a glance
03Original abstract
This is a single-case report of the syndrome of Tourette's disorder (GTS) and infantile autism (IA) occurring together. Neuroleptics were not administered prior to the onset of GTS. The heuristic value of comparing the different biochemical mechanisms of the syndromes and its implication for diagnosis and etiology is discussed. Norepinephrine is thought to be at least one transmitter that differentiates the syndromes.
Journal of autism and developmental disorders, 1982 · doi:10.1007/BF01538324