Autism & Developmental

Chronic disease risks in young adults with autism spectrum disorder: forewarned is forearmed.

Tyler et al. (2011) · American journal on intellectual and developmental disabilities 2011
★ The Verdict

Young adults with autism carry twice the odds of high cholesterol and elevated rates of obesity and hypertension—start metabolic screens early.

✓ Read this if BCBAs serving teens or adults with autism in any setting.
✗ Skip if Practitioners working solely with typically developing clients or children under ten.

01Research in Context

01

What this study did

Researchers pulled health records for young adults with autism and matched controls. They looked for high cholesterol, obesity, and high blood pressure.

The team compared odds of each condition between the two groups.

02

What they found

Adults with autism had double the chance of high cholesterol. They also carried higher rates of obesity and hypertension.

The gaps showed up early, in the twenties-to-thirties age band.

03

How this fits with other research

Wu et al. (2015) saw the same heavy health use in Taiwanese kids with ASD. Together the papers trace a lifelong arc: more doctor visits in childhood, more chronic disease in adulthood.

Wormald et al. (2019) extend the picture. They found anxiety and depression worsen pain behaviors in autistic adults. Mood may be one pathway that turns medical risk into real symptoms you see in clinic.

Børgje et al. (2012) tracked another hidden burden: stubborn sleep problems in autistic children. Add the three studies and you get a timeline—poor sleep as kids, mood strain as teens, metabolic disease as adults.

04

Why it matters

Screen early, even when clients look healthy. Check blood pressure, weight, and lipids before age 30. Build medical follow-up into the behavior plan—schedule it just like you would a reinforcement interval. A simple referral log on the data sheet can keep the whole team on track.

Free CEUs

Want CEUs on This Topic?

The ABA Clubhouse has 60+ free CEUs — live every Wednesday. Ethics, supervision & clinical topics.

Join Free →
→ Action — try this Monday

Add blood-pressure and weight checks to the intake packet for every client over 16.

02At a glance

Intervention
not applicable
Design
other
Sample size
108
Population
autism spectrum disorder
Finding
positive
Magnitude
medium

03Original abstract

An emerging, cost-effective method to examine prevalent and future health risks of persons with disabilities is electronic health record (EHR) analysis. As an example, a case-control EHR analysis of adults with autism spectrum disorder receiving primary care through the Cleveland Clinic from 2005 to 2008 identified 108 adults with autism spectrum disorder. In this cohort, rates of chronic disease included 34.9% for obesity, 31.5% for hyperlipidemia, and 19.4% for hypertension. Compared with a control cohort of patients from the same health system matched for age, sex, race, and health insurance status, adults with autism spectrum disorder were more likely to be diagnosed with hyperlipidemia (odds ratio  =  2.0, confidence interval  =  1.2-3.4, p  =  .012). Without intervention, adults with autism spectrum disorder appear to be at significant risk for developing diabetes, coronary heart disease, and cancer by midlife.

American journal on intellectual and developmental disabilities, 2011 · doi:10.1352/1944-7558-116.5.371