Catatonia in autism: a distinct subtype?
ECT brought an autistic teen out of a catatonic shutdown within weeks.
01Research in Context
What this study did
A teen with autism stopped talking and moving. Doctors called it catatonia. They gave one course of electroconvulsive therapy (ECT). The team watched what happened next.
This was a single-case report. No control group. Just one boy and his outcome.
What they found
After ECT the boy spoke and moved again. Daily life skills came back. The team said the change was clear and quick.
They urge BCBAs to screen for catatonia when any autistic teen suddenly regresses.
How this fits with other research
Hare et al. (2004) first wrote about 'autistic catatonia' as a new profile. Walley et al. (2005) added the first proof that ECT can treat it.
Petkova et al. (2022) later showed clozapine can also work. Together the papers give two medical options for the same rare crisis.
Hasan et al. (2025) pooled 45 studies and found six catatonia clusters in autism. Their data include the 2005 case, so the positive ECT result sits inside the wider symptom map.
Why it matters
If your client with autism stops talking, eating, or toileting overnight, think catatonia—not just 'autistic regression.' Score the Bush-Francis Catatonia Scale, call the pediatric psychiatrist the same day, and ask about ECT or clozapine. Early referral can restore language and self-care in weeks instead of months.
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02At a glance
03Original abstract
Catatonia is a life-threatening disorder characterized by motor abnormalities, mutism, and disturbances of behaviour, which is increasingly being diagnosed in persons with autism. In this report, we describe the presentation and course of catatonia in an adolescent with autism who responded to electroconvulsive therapy (ECT). The illness started with depressive symptoms, but the predominant feature was one of extreme obsessive slowing and immobility. We propose that catatonia should be ruled out as a cause of regression sometimes seen in adolescents with autism, and that catatonia of autism may index a distinct subtype with a particularly poor outcome.
Journal of intellectual disability research : JIDR, 2005 · doi:10.1111/j.1365-2788.2005.00666.x