Autism & Developmental

Behavior problems of children with Down syndrome and life events.

Coe et al. (1999) · Journal of autism and developmental disorders 1999
★ The Verdict

Life stress at home amplifies parent-reported attention and withdrawal problems in Down syndrome, but teachers don’t see the same spike.

✓ Read this if BCBAs assessing kids with Down syndrome in clinic or home settings
✗ Skip if Clinicians only serving autistic clients without Down syndrome

01Research in Context

01

What this study did

The team compared kids with Down syndrome to matched peers. They asked moms and teachers to rate behavior problems. They also tracked recent life events like moves or divorces.

The goal was to see if life stress made behavior issues worse in Down syndrome.

02

What they found

Kids with Down syndrome showed more attention, compliance, and social withdrawal problems. Life events only linked to mom reports, not teacher reports.

In short, stress at home worsened parent-rated problems, but school ratings stayed flat.

03

How this fits with other research

van Timmeren et al. (2016) extends these findings by showing the same attention problems hurt classroom task completion. McCarron et al. (2002) adds a timeline: externalizing behaviors drop with age while withdrawal rises, especially in teens.

Sasson et al. (2022) splits the Down syndrome group into three ASD-symptom profiles, showing social withdrawal clusters vary widely. Soltani et al. (2025) looks forward, finding poor working memory predicts later inattention six months out.

Taken together, the 1999 snapshot now sits inside a larger story: attention and withdrawal issues are early flags that can snowball into academic and later behavior risk.

04

Why it matters

You can’t treat what you don’t track. Screen for life stress during parent interviews and add a quick withdrawal checklist at intake. When home stress is high, boost parent training and respite referrals. Pair this with teacher data to spot cross-setting gaps early.

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Add a three-question life-events box to your parent intake form.

02At a glance

Intervention
not applicable
Design
quasi experimental
Sample size
44
Population
down syndrome
Finding
negative

03Original abstract

Behavior problems of 44 children with Down syndrome between the ages of 6 and 15 and 44 controls without mental retardation matched for age, sex, and socioeconomic status were compared on the basis of mother and teacher ratings. Ratings from both sources indicated that children with Down syndrome had more behavior problems, in particular attention deficit, noncompliance, thought disorder, and social withdrawal. Life events from the past year were significantly associated with mother but not teacher ratings of Down syndrome behavior problems.

Journal of autism and developmental disorders, 1999 · doi:10.1023/a:1023044711293