Autism Spectrum Disorder and Psychiatric Comorbidity in a Patient with Myhre Syndrome.

Doctors wrote up one young adult who has both Myhre syndrome and high-functioning autism.

They used ADOS-2 and ADI-R to check if the autism label fit.

No treatment was tested; the paper just shows how the two conditions can appear together.

The tests confirmed ASD in a person already known to have Myhre syndrome.

The authors warn that you can miss either diagnosis if you only look at the genetic label.

Moss et al. (2009) reviewed many genetic syndromes and found that ASD-like traits often look different from plain ASD. The new Myhre case adds one more rare syndrome to that list.

Mattila et al. (2010) counted that 74 % of youth with high-functioning ASD already carry extra psychiatric labels. The single Myhre case lines up with this pattern.

Mammarella et al. (2022) reported ASD in 48,XXYY syndrome using the same one-person method. Both papers show rare chromosomal disorders can hide beneath an ASD presentation.

When you see a client with a rare genetic diagnosis, do not assume all social quirks come from that syndrome. Run gold-standard autism tools if social-communication red flags appear. Catching both labels early guides better goals and saves re-assessment later.