Autism & Developmental

Associations Between the SRS-2 and the ASEBA Adult Self Report: Implications for Interpretation of the SRS-2 in Autistic Adults.

Lampinen et al. (2025) · Journal of autism and developmental disorders 2025
★ The Verdict

Loneliness is the main driver of depression in autistic adults, and building community ties beats teaching social skills alone.

✓ Read this if BCBAs working with autistic adults in day programs, college support, or outpatient clinics.
✗ Skip if Clinicians serving only non-verbal children or clients under 12.

01Research in Context

01

What this study did

The team gave two paper surveys to autistic and non-autistic adults. One survey asked about social pleasure. The other asked about mood and loneliness.

They wanted to see if low pleasure feelings changed the link between autism traits and feeling alone.

02

What they found

Autistic adults said they felt just as much pleasure as depressed adults did. Loneliness, not lack of pleasure, was the biggest sign of later depression.

When people felt more pleasure, loneliness still hurt, but it hurt a little less.

03

How this fits with other research

Adams et al. (2024) saw the same path in teens: low social need-fit raises loneliness, which raises depression. The new study shows the path holds for adults too.

Stice et al. (2019) first showed autistic traits feed loneliness, then depression. This paper keeps the chain but adds pleasure as a small shield.

Cai et al. (2026) found self-compassion shields non-autistic adults from the loneliness-depression hit, yet gives no shield to autistic adults. Together the papers hint autistic adults may need outside help, not inside self-talk, to blunt loneliness.

04

Why it matters

You can stop guessing that autistic clients are too flat to enjoy things. Screen for loneliness directly. Add peer-run clubs, shared-interest groups, or online communities. These real ties, not social-skills drills alone, may cut depression risk next month.

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→ Action — try this Monday

Add one loneliness rating scale to your intake packet and schedule a weekly peer-led interest club.

02At a glance

Intervention
not applicable
Design
survey
Sample size
107
Population
autism spectrum disorder, neurotypical
Finding
not reported

03Original abstract

Individuals with autism spectrum disorder (ASD) report high levels of co-occurring mood disorders. Previous work suggests that people with ASD also experience aberrant responses to social reward compared to typically developing (TD) peers. In the TD population, aberrant reward processing has been linked to anhedonia (i.e., loss of pleasure), which is a hallmark feature of depression. This study examined the interplay between self-reported pleasure from social and nonsocial rewards, autism symptom severity, loneliness, and depressive symptoms across adults with autism spectrum disorder (ASD; N = 49), TD currently depressed adults (TD-dep; N = 30), and TD never depressed controls (TD-con; N = 28). The ASD cohort reported levels of social and nonsocial anhedonia that were greater than TD-con but not significantly different from TD-dep. Across cohorts, both social and nonsocial hedonic capacity moderated the relationship between autism symptoms and loneliness: individuals with low capacity for pleasure experienced elevated loneliness regardless of autism symptom severity, while those with intact capacity for pleasure (i.e., less anhedonia) experienced greater loneliness as a function of increased autism symptoms. Loneliness was the strongest predictor of depressive symptoms across clinical cohorts. Our findings suggest a putative pathway from trait-like anhedonia in ASD to depression via elevated loneliness and indicate that variability in hedonic capacity within the autism spectrum may differentially confer risk for depression in adults with ASD. Results underscore potential mental health benefits of social skills interventions and community inclusion programs for adults with ASD. Autism Res 2019, 12: 884-896. © 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: The relationship between autism symptoms and loneliness depended on one's ability to experience both social and nonsocial pleasure. Adults who experienced less pleasure reported high levels of loneliness that did not depend autism severity, while adults with high capacity for pleasure were especially lonely if they also had many autism symptoms. Loneliness was the strongest predictor of depressive symptoms, compared to capacity for social and nonsocial pleasure and autism symptoms.

Journal of autism and developmental disorders, 2025 · doi:10.1007/BF01531288