Assessment & Research

Typical and atypical neurodevelopment for face specialization: an FMRI study.

Joseph et al. (2015) · Journal of autism and developmental disorders 2015
★ The Verdict

Face specialization grows along different brain tracks in autism and siblings, so typical social-attention scores can hide atypical wiring.

✓ Read this if BCBAs who assess or teach social skills to school-age clients with autism.
✗ Skip if Clinicians working only with toddlers or adults.

01Research in Context

01

What this study did

The team scanned kids' brains while they looked at faces. They used fMRI to watch which areas lit up.

They tested three groups: typical kids, kids with autism, and autism siblings. All were school age.

02

What they found

All groups got better at face recognition as they aged. But their brains took different roads to get there.

Kids with autism used unusual networks. Siblings showed extra activation, like their brains were compensating.

03

How this fits with other research

Hsieh et al. (2014) found no eye-gaze differences when kids looked at faces in picture symbols. The new fMRI data says the brain still wires differently. The clash is about the task: symbols versus real faces.

Mamashli et al. (2021) showed weaker brain connectivity in autism when kids viewed upside-down faces. Austin et al. (2015) extends that work by mapping the whole developmental arc, not just one moment.

Deruelle et al. (2004) first spotted that kids with autism prefer local face details. The 2015 study now shows the neural growth pattern behind that bias.

04

Why it matters

A child may look at your face but still be using an atypical brain route. Keep this in mind when you interpret social-attention probes or teach face-emotion skills. If progress seems slow, the brain may need more time or a different cue, not more drills.

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Add a brief inverted-face trial to your social-attention probe and note any extra struggle.

02At a glance

Intervention
not applicable
Design
other
Population
autism spectrum disorder, neurotypical, mixed clinical
Finding
not reported

03Original abstract

Individuals with autism spectrum disorder (ASD) and their relatives process faces differently from typically developed (TD) individuals. In an fMRI face-viewing task, TD and undiagnosed sibling (SIB) children (5-18 years) showed face specialization in the right amygdala and ventromedial prefrontal cortex, with left fusiform and right amygdala face specialization increasing with age in TD subjects. SIBs showed extensive antero-medial temporal lobe activation for faces that was not present in any other group, suggesting a potential compensatory mechanism. In ASD, face specialization was minimal but increased with age in the right fusiform and decreased with age in the left amygdala, suggesting atypical development of a frontal-amygdala-fusiform system which is strongly linked to detecting salience and processing facial information.

Journal of autism and developmental disorders, 2015 · doi:10.1007/s10803-014-2330-4