Assessment & Research

Successful aging in a 70-year-old man with down syndrome: a case study.

Krinsky-McHale et al. (2008) · Intellectual and developmental disabilities 2008
★ The Verdict

One young learners with Down syndrome stayed dementia-free and independent for 16 years, proving decline is not a given.

✓ Read this if BCBAs writing adult day-program or residential goals for clients with Down syndrome.
✗ Skip if Practitioners who work only with young children or ASD without Down syndrome.

01Research in Context

01

What this study did

Doctors followed one man with Down syndrome for 16 years. He was 54 when they started and 70 at the end.

They gave him memory tests, checked his daily living skills, and looked for signs of dementia at each visit.

02

What they found

The man kept the same test scores year after year. He still cooked, shopped, and rode the bus alone at 70.

No dementia appeared, even though most people with Down syndrome his age show serious decline.

03

How this fits with other research

Rose et al. (2000) tracked a whole county of adults with Down syndrome. They saw high dementia risk starting in the 30s. The new case looks opposite, but the older study covered everyone while this one spotlights a rare high achiever.

Yuwiler et al. (1992) watched 30- to young learners for five years and found stable scores. Their work sets the stage for the young learners’s story: stability can last decades longer than expected.

McLennan et al. (2008) showed that behavior problems, not memory slips, usually trigger dementia referrals. Our man never acted out, so he flew under the radar.

04

Why it matters

This single case widens the goalposts. When you plan for adults with Down syndrome, don’t assume steep decline is inevitable. Keep goals ambitious, teach new skills, and monitor behavior changes instead of relying only on memory tests.

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02At a glance

Intervention
not applicable
Design
case study
Sample size
3
Population
down syndrome
Finding
not reported

03Original abstract

The authors present a case study of a 70-year-old man with Down syndrome ("Mr. C.") who they followed for 16 years and who does not exhibit declines in cognitive or functional capacities indicative of dementia, despite having well-documented, complete trisomy 21. The authors describe the age-associated changes that occurred over 16 years as well as provide detailed information regarding Mr. C.'s health and genetic status. To further emphasize Mr. C.'s successful aging, the authors compared his longitudinal performance profile with that of 2 peers of comparable level of intellectual functioning: 1 similar-aged man with clinical Alzheimer's disease and a younger man who was healthy. The authors present potential explanations for the phenotypic variability observed in individuals with Down syndrome.

Intellectual and developmental disabilities, 2008 · doi:10.1352/2008.46:215-228