Sex-Differences in Children Referred for Assessment: An Exploratory Analysis of the Autism Mental Status Exam (AMSE).
The 8-item AMSE is sex-fair overall, but girls with ASD shine on language items while boys pop on sensory ones.
01Research in Context
What this study did
The team looked at 8-item Autism Mental Status Exam scores for kids sent for ASD testing. They asked: do girls and boys score differently on these brief items? The sample was mixed-age children referred to clinics.
What they found
Girls with ASD were more likely to show language deficits on the AMSE. Boys showed more sensory symptoms. Yet the tool's overall ability to flag autism was the same for both sexes.
How this fits with other research
Kocher et al. (2015) saw no sex differences in toddlers using broad developmental measures. The new study used the AMSE and found small item-level gaps, showing the tool, not the kids, drives what you spot.
Ros-Demarize et al. (2020) also saw girls score higher on social-communication items in toddlers. Together the papers hint that girls' social struggles stand out while their restricted interests hide.
Giofrè et al. (2014) proved the AMSE works well in verbally fluent adults. Burrows et al. (2018) extend that work down to children and add the sex lens, keeping the tool's overall validity intact.
Why it matters
You can keep using the 8-item AMSE for both boys and girls; it does not under-detect either sex. Just remember that a girl with weak language or a boy with sensory quirks may simply be showing the pattern this study captured. Let those item hints guide your follow-up questions, not your final verdict.
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02At a glance
03Original abstract
The autism mental status exam is an eight-item observational assessment that structures the way we observe and document signs and symptoms of ASD. Investigations of test performance indicate strong sensitivity and specificity using gold-standard assessment as reference standard. This study aims to explore potential sex differences in AMSE test performance and observations of 123 children referred for autism assessment. Results indicates more language deficits in females with ASD than in males with ASD and less sensory symptoms in females compared to males with ASD. The AMSE performance is similar in identifying ASD and non-ASD in females compared to males. Less disruptive behaviors in females, might cause a need for a bigger hit to other areas of development to raise concern.
Journal of autism and developmental disorders, 2018 · doi:10.1007/s10803-018-3488-y