Serum Ischemia-Modified Albumin Levels, Myeloperoxidase Activity and Peripheral Blood Mononuclear cells in Autism Spectrum Disorder (ASD).

Doctors took one tube of blood from the kids with autism and 40 matched kids without. They measured three things: ischemia-modified albumin (IMA), myeloperoxidase (MPO), and white-blood cells called mononuclear cells.

Higher numbers mean more oxidative stress and inflammation. The team used simple lab machines and compared group averages.

Autism group had 1.5 times more IMA, double the MPO activity, and a large share more mononuclear cells. All differences were large enough to be unlikely by chance.

No child had an infection that day, so the jumps point to ongoing immune and oxidative stress.

Mukherjee et al. (2015) warned that shiny new biomarkers are useless without solid behavior data. Fatih’s blood numbers fit that call: they are only helpful if you pair them with good ADOS and VB-MAPP scores.

Lyall et al. (2025) show Black children get missed in clinic even when autism traits are high. Adding a quick blood test might reduce that gap by giving doctors a second, less biased flag.

Tost et al. (2024) used EEG instead of blood and also found biological signals that change with input. Together these papers say: body metrics (blood or brain waves) can add evidence, but they do not replace watching the child.

You can’t run labs in a classroom, but you can ask the pediatrician for these cheap tests when a medical work-up is already planned. If numbers come back high, share them with the team to support earlier diagnosis or to document inflammation before starting diet or medication trials. Keep scoring behaviors the same way—blood is just an extra data point, not a crystal ball.