Prader-Willi syndrome and psychotic symptoms: 2. A preliminary study of prevalence using the Psychopathology Assessment Schedule for Adults with Developmental Disability checklist.

The team gave adults with Prader-Willi syndrome a short checklist. The tool is called PAS-ADD. It screens for signs of psychosis.

Staff asked 16 questions about hallucinations, delusions, and mood. They wanted a quick yes-or-no picture of mental-health risk.

Six out of every 100 adults flagged possible psychotic disorder. The authors say this rate is above chance.

The result is only a first estimate. It tells clinicians the issue is common enough to watch for.

Saima et al. (2022) later showed sensory problems in the same group. Hard-to-handle sights and sounds went hand in hand with autism-like behaviors. Together the studies say: screen both psychosis and sensory issues.

Dimitropoulos et al. (2013) found that certain genetic subtypes of PWS score just as high on social impairment as people with ASD. The 1998 psychosis data and the 2013 social data line up—both urge early psychiatric care.

Walley et al. (2005) looked at executive function in adults with PWS and found no clear deficit. That seems to clash with Estival et al. (2021), who later reported poor planning. The gap is about method: M et al. used brief IQ-style tasks, while Séverine used real-life planning games. Different tests, different answers.

You now have a one-page tool to flag psychosis risk in PWS. Add it to your intake packet. If the score is high, refer for full psychiatric evaluation and list sensory and social screens next.