Assessment & Research

Neurodevelopmental Outcomes of Pediatric Cardiac Extracorporeal Membrane Oxygenation Survivors With Central Cannulation.

Nakip et al. (2024) · American journal on intellectual and developmental disabilities 2024
★ The Verdict

Most kids who survive heart surgery on ECMO will have developmental delays, so plan assessments early no matter how long the ECMO run lasted.

✓ Read this if BCBAs and RBTs serving infants or toddlers after cardiac ICU care.
✗ Skip if Clinicians who only treat typically developing children.

01Research in Context

01

What this study did

Doctors looked at kids who lived after heart surgery on ECMO. ECMO is a machine that breathes and pumps blood for you.

They wrote down how many kids later had motor, thinking, or other delays. They also checked if longer ECMO time or younger age made delays worse.

02

What they found

Most kids had delays. Eight out of every ten had some developmental delay. Six out of ten had trouble moving. Seven out of ten had trouble thinking.

Surprisingly, kids who were on ECMO longer did not do worse. Babies put on ECMO at younger ages did not do worse either.

03

How this fits with other research

Tsai et al. (2014) saw that very small babies on ventilators for more than two weeks had higher cerebral-palsy risk. Saritas did not find that longer machine time hurt kids. The difference is the machine: ventilator vs ECMO.

Horovitz et al. (2011) showed that toddlers with global delay walk later than those with only seizures or prematurity. Saritas adds cardiac-ECMO survivors to the list of kids who will likely need early motor help.

Wang et al. (2022) used brain-stem tests to spot future ASD. Saritas used simple bedside notes. Both push for early checks so therapy can start sooner.

04

Why it matters

If you work with infants after heart surgery, expect delays even if ECMO lasted only a few days. Start physical, occupational, and speech referrals before discharge. Track milestones every few months. Early services can change the child’s long-term path.

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→ Action — try this Monday

Add ECMO history to your intake form and schedule a baseline developmental screen within the first month home.

02At a glance

Intervention
not applicable
Design
case series
Population
developmental delay
Finding
not reported

03Original abstract

Extracorporeal life support, such as pediatric cardiac extracorporeal membrane oxygenation (ECMO), is associated with significant mortality and morbidity risk. This study evaluated cardiac ECMO survivors with central cannulation and found that 51.1% were discharged from the hospital. The study also revealed high rates of developmental delay (82.7%), motor dysfunction (58.8%), and cognitive dysfunction (70.6%) among survivors. No significant correlation was found between the duration of ECMO, age at ECMO, pre-ECMO maximum lactate levels, and cognitive scores. Participants with motor dysfunction were significantly younger (p = 0.04). PRISM scores of those with an abnormal developmental status were significantly higher (p = 0.03). Logistic regression analysis did not show a significantly increased risk. Factors such as age, disease severity, and ECMO itself were identified as potential contributors to neurodevelopmental delay.

American journal on intellectual and developmental disabilities, 2024 · doi:10.1352/1944-7558-129.5.377