Multisite study of new autism diagnostic interview-revised (ADI-R) algorithms for toddlers and young preschoolers.
New toddler ADI-R rules give valid autism flags for kids as young as 12 months—update your diagnostic flow now.
01Research in Context
What this study did
Tureck et al. (2013) tested new ADI-R rules made just for toddlers and young preschoolers.
They ran the new rules at many clinics to see if scores still flagged autism correctly.
Kids as young as 12 months with a nonverbal mental age of at least 10 months took part.
What they found
The toddler rules kept the good sensitivity and specificity of the old rules.
A clean three-factor structure held up across sites.
Clinicians can now trust the ADI-R for kids under four.
How this fits with other research
Braam et al. (2008) first showed the old two-factor ADI-R needed fixing. Their work led to the 2013 toddler update.
Mulder et al. (2020) trimmed items on the SCQ and SRS-2 for fragile-X. Both papers prove that small rule tweaks boost accuracy.
Bouck et al. (2016) warn that wide confidence intervals plague two-phase prevalence studies. The tighter toddler ADI-R rules help shrink that uncertainty.
Why it matters
If you assess toddlers, swap in the 2013 algorithms. You will get reliable autism flags without waiting for older preschool norms. Update your interview scripts and training materials this month.
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02At a glance
03Original abstract
Using two independent datasets provided by National Institute of Health funded consortia, the Collaborative Programs for Excellence in Autism and Studies to Advance Autism Research and Treatment (n = 641) and the National Institute of Mental Health (n = 167), diagnostic validity and factor structure of the new Autism Diagnostic Interview (ADI-R) algorithms for toddlers and young preschoolers were examined as a replication of results with the 2011 Michigan sample (Kim and Lord in J Autism Dev Disord 42(1): 82-93, 2012). Sensitivities and specificities and a three-factor solution were replicated. Results suggest that the new ADI-R algorithms can be appropriately applied to existing research databases with children from 12 to 47 months and down to nonverbal mental ages of 10 months for diagnostic grouping.
Journal of autism and developmental disorders, 2013 · doi:10.1111/j.1469-7610.2005.01434.x