Assessment & Research

Long‐term functional stability of problem behavior exposed to psychotropic medications

Cox et al. (2022) · Journal of Applied Behavior Analysis 2022
★ The Verdict

Antipsychotic dose changes rarely move problem behavior, so keep your FA active and stick with reinforcement plans.

✓ Read this if BCBAs working with clients on antipsychotics in residential or clinic settings
✗ Skip if Practitioners serving clients with no psychotropic medications

01Research in Context

01

What this study did

Cox et al. (2022) watched problem behavior while doctors changed antipsychotic doses. They ran a continuous functional analysis before, during, and after each change.

The team worked with people who had intellectual or developmental disabilities. They wanted to know if the behavior’s function shifted when the drug dose went up or down.

02

What they found

Across 14 different dose tweaks, behavior barely budged. The function stayed the same even when the dose changed.

Small drops in problem behavior showed up, but they were tiny. The data say the medicine edits did not rewrite why the behavior happened.

03

How this fits with other research

Northup et al. (1991) also used functional analysis with people with ID. They saw big, quick drops in aggression when the reinforcer was switched to a new response. Cox sees almost zero change when only the pill changes, showing contingencies trump dose tweaks.

Matson et al. (1999) reviewed piles of studies and found that after an FA, teams pick reinforcement plans, not more drugs. Cox’s data back that up: if the function holds steady, behavior-based treatment stays the right call.

Hutchins et al. (2020) saw antipsychotics hurt gait in adults with ID. Cox shows the same drugs barely touch behavior. Together, the papers hint the meds give little gain and some motor cost.

04

Why it matters

You can stop waiting for the next med change to fix problem behavior. Run your FA, see the function, and build a behavior plan right away. Keep the analysis in place after each dose tweak so you catch any real shift early and avoid months of useless tinkering.

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→ Action — try this Monday

Re-run one FA condition after the next med change to confirm the function is still the same.

02At a glance

Intervention
functional analysis
Design
single case other
Sample size
4
Population
intellectual disability, developmental delay
Finding
null
Magnitude
negligible

03Original abstract

Psychopharmacological and behavioral interventions are often combined in the treatment of problem behavior in people with intellectual and developmental disability (IDD). However, little is known about the interaction between medication pharmacodynamics and behavior function. A better understanding of these mechanisms could serve as the conceptual foundation for combined interventions. The current analysis is a systematic replication of Valdovinos et al. (2009). We conducted continuous functional analyses within analogue reversal and parametric analyses monitoring the impact of various dosages of primarily antipsychotic medications on problem behavior and its function. Four individuals with IDD and problem behavior who were also receiving psychotropic medications participated. Medication adjustments produced small to negligible decreases in problem behavior, and behavior function remained largely unchanged through the 14 medication adjustments evaluated. The continuous functional analysis helped to identify what could be delayed medication effects on problem behavior. The clinical and methodological implications of this replication are discussed.

Journal of Applied Behavior Analysis, 2022 · doi:10.1002/jaba.873