Interactions between behavior function and psychotropic medication.
Psychotropic meds usually cut problem behavior but can switch its function, so rerun your FA after any med change.
01Research in Context
What this study did
The authors pulled 37 published cases where kids got both a functional analysis and a new psychotropic med. They re-examined the data to see if the drug changed the behavior's function.
The group was mixed: autism, ID, ADHD, and other diagnoses. All had severe problem behavior like SIB or aggression.
What they found
In 29 of the 37 cases the med lowered problem behavior but kept the same function. Escape, attention, or tangible control still drove the behavior, just less of it.
In 4 cases the function itself shifted. For example, escape-maintained SIB became attention-maintained. That means your old FCT plan could miss the mark.
How this fits with other research
Simó-Pinatella et al. (2013) showed that changing a motivating operation (like giving free attention) usually keeps the same function but alters strength. Spriggs et al. (2016) find the same pattern with meds: most of the time the function stays, only the volume drops.
Spackman et al. (2025) and Schieltz et al. (2022) ran telehealth FAs and got clean functions before starting FCT. Their success hinges on a stable function. D et al. warn that a new prescription could flip that function and wreck the treatment plan.
Hake et al. (1983) mixed Dexedrine with self-control training and saw added benefits. D et al. agree meds can help, but add a caution: rerun your FA after any dose change so your behavioral program still matches the real function.
Why it matters
Before you write a behavior plan, ask the family if meds have changed in the last month. If they have, run a brief re-analysis or at least probe the old conditions. A five-minute attention test could save you weeks of ineffective intervention.
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02At a glance
03Original abstract
We reanalyzed published studies that reported functional analyses conducted in the presence and absence of medication. In Analysis 1, we assessed the overall effect of psychotropic medication on problem behavior. Medication had a reductive effect in 29 of the 37 sets of functional analyses reviewed. The magnitude of the effect was associated with the baseline level of responding according to a rate-dependency function. Analysis 2 examined medication-induced changes in behavior function. The introduction of medication was followed by the emergence of a new function (1), a change in functions (1), the subtraction of one function in multiply controlled problem behavior (2), and near-zero levels of responding (6). Thus, in 4 of 37 cases reviewed, medication may have induced function-specific changes in problem behavior. We discuss the implications of these findings for a closer collaboration between behavior analysts and prescribing professionals in the treatment of problem behavior.
Journal of applied behavior analysis, 2016 · doi:10.1002/jaba.247