Assessment & Research

Examining reports of mental health in adults with Williams syndrome.

Stinton et al. (2012) · Research in developmental disabilities 2012
★ The Verdict

Adults with Williams syndrome give trustworthy self-reports that reveal more anxiety than caregivers report, so ask them directly.

✓ Read this if BCBAs completing adult assessments or writing anxiety interventions for clients with Williams syndrome.
✗ Skip if Practitioners who work only with young children or who do not serve clients with genetic syndromes.

01Research in Context

01

What this study did

Oliver et al. (2012) talked directly to adults with Williams syndrome. They asked each adult how anxious they felt. They also asked caregivers to rate the same adult's anxiety. Then they gave everyone a quick Stroop test that flashed anxiety words like 'worry' or neutral words like 'table'.

The team wanted to know if adults with WS could report their own mental health reliably, or if caregivers alone should speak for them.

02

What they found

Adults with WS reported more anxiety than their caregivers noticed. The Stroop results backed this up: the adults noticed anxiety words faster, a sign they were on high alert for threat.

Bottom line: people with WS can tell you when they are anxious, and they often see it more clearly than caregivers do.

03

How this fits with other research

Uljarević et al. (2018) later showed that two things drive that anxiety: intolerance of uncertainty and sensory hypersensitivity. Their parent survey extends Chris et al. by pointing to clear treatment targets.

Ahlborn et al. (2008) saw the same anxiety pattern in young children. Kids with WS startled and covered their ears at mild sounds, hinting that the worry pathway starts early and stays across the lifespan.

Hwang et al. (2020) found a near-identical uncertainty-anxiety link in autistic adults. The pathway looks the same in two different diagnoses, so tackling intolerance of uncertainty may help both groups.

04

Why it matters

If you assess an adult with Williams syndrome, add a short anxiety self-report to your intake. Do not rely only on caregiver forms. Ask about everyday uncertainty and sensory triggers while you are at it. These quick questions can steer you toward coping-skills training, graded exposure, or sensory supports that earlier papers show ease WS anxiety.

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Add two anxiety self-rating questions to your adult intake form for any client with Williams syndrome.

02At a glance

Intervention
not applicable
Design
case series
Sample size
19
Population
other
Finding
positive

03Original abstract

Prior research suggests that individuals with Williams syndrome (WS) have a disposition towards anxiety. Information regarding this is typically derived from parents and carers. The perspectives of the individuals with WS are rarely included in research of this nature. We examined the mental health of 19 adults with WS using explicit (psychiatric interview) and implicit (modified Stroop task) measures and compared informant (parents/carers) and respondent (adults with WS) reports of psychiatric symptoms. Informants and respondents both reported more symptoms of anxiety (n=7-9) than depression (n=2). Strong positive correlations were found between informant and respondent reports of symptoms of mental health problems. Compared to informants, respondents reported significantly more symptoms overall and somewhat more symptoms of anxiety. Results from the Stroop task indicated that the adults with WS were more vigilant to anxiety-related words than to depression-related words. The adults with WS provided reliable information regarding their mental health, thus providing further evidence that anxiety is part of the behavioural phenotype of the syndrome.

Research in developmental disabilities, 2012 · doi:10.1016/j.ridd.2011.09.002