Divergent patterns of social cognition performance in autism and 22q11.2 deletion syndrome (22q11DS).
Autistic teens can read emotions accurately while using unusual eye paths, a compensatory pattern not seen in 22q11DS.
01Research in Context
What this study did
The team compared three groups of teens: autistic, 22q11.2 deletion syndrome, and typically developing. Each teen watched faces on a screen and named the emotion. An eye-tracker recorded where they looked.
The goal was to see if social-cognition problems look the same in autism and 22q11DS, or if each condition has its own pattern.
What they found
Both autism and 22q11DS groups scored lower on face-emotion accuracy and looked less at the eye region than typical peers.
Only the autistic teens also scanned non-social parts of scenes less, yet they still hit typical accuracy. This hints they use a different visual route to reach the right answer.
How this fits with other research
Wang et al. (2022) extends the eye-tracking link: poor sleep in young autistic kids worsens core symptoms through the same atypical gaze patterns L et al. saw.
Kiep et al. (2017) shows girls with autism camouflage social gaps by staying near peers. L et al. adds a new camouflage route—odd scanning that still lets teens name emotions correctly.
Laermans et al. (2025) now supersedes the single-task view. Their 2025 model says social competence in autistic teens is a network of brain, cognition, and behavior together, not eye gaze alone.
Why it matters
If a teen looks away from eyes yet labels emotions fine, don’t assume lack of skill. Probe for compensatory tactics before adding eye-contact goals. Pair this info with sleep data and wider social-brain measures to build a fuller picture of social strengths and needs.
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02At a glance
03Original abstract
Individuals with developmental disorders frequently report a range of social cognition deficits including difficulties identifying facial displays of emotion. This study examined the specificity of face emotion processing deficits in adolescents with either autism or 22q11DS compared to typically developing (TD) controls. Two tasks (face emotion recognition and weather scene recognition) were used to explore group differences in visual scanpath strategy and concurrent recognition accuracy. For faces, the autism and 22q11DS groups demonstrated lower emotion recognition accuracy and fewer fixations compared to the TD group. Individuals with autism demonstrated fewer fixations to some weather scene stimuli compared to 22q11DS and TD groups, yet achieved a level of recognition accuracy comparable to the TD group. These findings provide evidence for a divergent pattern of social cognition dysfunction in autism and 22q11DS.
Journal of autism and developmental disorders, 2013 · doi:10.1007/s10803-012-1742-2