Brief report: effect of maternal age on severity of autism.
Mom's age at birth does not predict IQ or parent-rated autism severity, so cross it off your worry list.
01Research in Context
What this study did
Doctors tested 154 kids with autism who came to a clinic. They asked: does mom's age when the child was born link to how severe the autism is?
They looked at two things: IQ scores and parent ratings on the Child Behavior Checklist. They ran the numbers to see if older moms had kids with lower IQ or more social problems.
What they found
No link at all. Kids of 20-year-old moms looked the same as kids of 40-year-old moms on both IQ and parent-rated social severity.
The team concluded that maternal age is not a crystal ball for autism prognosis.
How this fits with other research
Robinson et al. (2011) asked the same question in the general population and also found nothing. Their null result backs up this clinic sample, giving a two-for-one replication.
Capio et al. (2013) clashes. In a huge Finnish cohort they saw advanced maternal age raise risk for Asperger's and PDD. The difference: they tracked autism risk at birth, not severity after diagnosis. Risk and severity are not the same thing.
Shire et al. (2022) extends the story. They swapped calendar age for 'biologic age' based on mom's DNA marks. Slight cognitive dips showed up in babies, hinting that age itself may matter less than how fast mom's cells are aging.
Why it matters
When parents ask, 'Will my age make my child's autism worse?' you can say the weight of evidence says no. Skip age-based scare talk. Spend your session time on skill-building programs, not on maternal age guilt.
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If parents bring up maternal age, show them these data and pivot to discussing today's teaching targets.
02At a glance
03Original abstract
The etiology of autism is complex, consisting of unknown genetic and environmental factors. Previous studies have revealed that maternal age is increased in autism compared to controls, making it a possible risk factor. This study examined the effects of maternal age on autism severity using IQ as a measure of cognitive severity and selected subtests of the Child Behavior Checklist (CBCL) as measures of social severity. A sample of 154 subjects with autism spectrum disorders was obtained from the Stanford Neuropsychiatry/Pervasive Developmental Disorder (PDD) clinic. Results indicate that there is no relationship between IQ or selected CBCL subtests and maternal age, suggesting that maternal age does not influence the severity of autism as measured by these indicators.
Journal of autism and developmental disorders, 2007 · doi:10.1007/s10803-006-0217-8